植物光信号途径重要新调控因子TZP的研究进展

doi:10.11983/CBB22076

植物学报 ›› 2022, Vol. 57 ›› Issue (5): 579-587.DOI: 10.11983/CBB22076

植物光信号途径重要新调控因子TZP的研究进展

李聪¹^,², 齐立娟¹, 谷晓峰², 李继刚¹^,^*()

¹中国农业大学生物学院, 植物生理学与生物化学国家重点实验室, 北京 100193
²中国农业科学院生物技术研究所, 北京 100081

收稿日期:2022-04-15 接受日期:2022-06-23 出版日期:2022-09-01 发布日期:2022-09-09
通讯作者: 李继刚
作者简介:*E-mail: jigangli@cau.edu.cn
基金资助:
国家自然科学基金(32000187)

Research Progress on TZP, a Novel Key Regulator of Light Signal Transduction in Plants

Li Cong¹^,², Qi Lijuan¹, Gu Xiaofeng², Li Jigang¹^,^*()

¹State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100193, China
²Biotechnology Research Institute, Chinese Academy of Agriculture Sciences, Beijing 100081, China

Received:2022-04-15 Accepted:2022-06-23 Online:2022-09-01 Published:2022-09-09
Contact: Li Jigang
About author:*E-mail: jigangli@cau.edu.cn

摘要/Abstract

摘要： TZP (TANDEM ZINC-FINGER/PLUS3)是近年来鉴定到的一个光信号转导途径新组分, 在光介导的植物生长发育过程中发挥重要调控作用。TZP不仅负调控蓝光信号途径, 参与光敏色素B (phyB)介导的开花调控过程, 还参与调控phyA在体内的蛋白质磷酸化。对TZP生化活性和作用机制的深入研究, 不仅有助于进一步完善光信号调控网络, 也可为设计和培育具有耐密理想株型及高光效作物新品种提供理论依据。该文系统总结了TZP在植物光信号途径中发挥的重要调控作用, 并提出未来TZP功能研究的重要问题。

关键词: TZP, 光信号转导, 光敏色素, 调控机制, 生化功能

Abstract: TANDEM ZINC-FINGER/PLUS3 (TZP) is a recently characterized novel key component of light signal transduction in plants. Accumulating evidence indicates that TZP plays an important role in multiple processes of light-mediated plant growth and development. TZP acts as a negative regulator of blue light signaling, regulates phytochrome B (phyB)-dependent control of photoperiodic flowering, and is required for the phosphorylation of the far-red light photoreceptor phyA in vivo. Further investigation and full elucidation of the biochemical activity and regulatory mechanisms of TZP will not only provide new insights into the light signaling networks, but also facilitate the design and breeding of new crop varieties with ideal plant architecture and more efficient usage of solar energy. In this review, we systematically summarized the current understanding of the role of TZP in regulating light signaling pathways in plants, and discussed the important questions for further study on TZP functions.

Key words: TZP, light signaling, phytochrome, regulatory mechanism, biochemical function

李聪, 齐立娟, 谷晓峰, 李继刚. 植物光信号途径重要新调控因子TZP的研究进展. 植物学报, 2022, 57(5): 579-587.

Li Cong, Qi Lijuan, Gu Xiaofeng, Li Jigang. Research Progress on TZP, a Novel Key Regulator of Light Signal Transduction in Plants. Chinese Bulletin of Botany, 2022, 57(5): 579-587.

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链接本文: https://www.chinbullbotany.com/CN/10.11983/CBB22076

https://www.chinbullbotany.com/CN/Y2022/V57/I5/579

图/表 2

图1 不同物种中TZP (TANDEM ZINC-FINGER/PLUS3)的系统进化分析 (A) TZP蛋白结构; (B) 利用ZF和PLUS3结构域对TZP进行的系统进化分析。不同物种中TZP蛋白的数据库(http://plants.ensembl. org/)登录号: 毛白杨(KAG6766194)、番木瓜(XP_021897044)、黄连木(XP_031272328)、枣树(XP_015887831)、葡萄(CBI26371)、中华猕猴桃(PSS33801)、烟草(XP_016434926)、石榴(XP_031396210)、榴莲(XP_022739593)、川桑(XP_024023066)、板栗(KAF3952474)、花生(QHO11257.1)、苜蓿(XP_003610789)、深山南芥(EFH41669)、拟南芥(At5g43630)、萝卜(XP_018477082)、白菜型油菜(XP_009101774.1)、甘蓝型油菜(KAH0868982)、黄瓜(XP_031738237)、二穗短柄草(KQK10007)、大麦(HORVU.MOREX.r3.3HG0292790)、水稻(Os01g0775100)、谷子(KQL07205)、高粱(KXG33485)、玉米(Zm00001eb151720)和水藓(KAH8943079)。

Figure 1 Phylogenetic analyses of TANDEM ZINC-FINGER/PLUS3 (TZP) from different plant species (A) The structure of TZP protein; (B) Phylogenetic analyses of TZP from different plant species using the ZF and PLUS3 domains. The database (http://plants.ensembl.org/) accession numbers of TZP protein sequences from different plant species: Populus tomentosa (KAG6766194), Carica papaya (XP_021897044), Pistacia vera (XP_031272328), Ziziphus jujube (XP_015887831), Vitis vinifera (CBI26371), Actinidia chinensis (PSS33801), Nicotiana tabacum (XP_016434926), Punica granatum (XP_031396210), Durio zibethinus (XP_022739593), Morus notabilis (XP_024023066), Castanea mollissima (KAF3952474), Arachis hypogaea (QHO11257.1), Medicago truncatula (XP_003610789), Arabidopsis lyrata (EFH41669), A. thaliana (At5g43630), Raphanus sativus (XP_018477082), Brassica rapa (XP_009101774.1), B. napus (KAH0868982), Cucumis sativus (XP_031738237), Brachypodium distachyon (KQK10007), Hordeum vulgare (HORVU.MOREX.r3.3HG0292790), Oryza sativa (Os01g0775100), Setaria italica (KQL07205), Sorghum bicolor (KXG33485), Zea mays (Zm00001eb151720), and Fontinalis antipyretica (KAH8943079).

图2 TZP (TANDEM ZINC-FINGER/PLUS3)在光信号转导途径中的调控功能在蓝光下, TZP与ZFHD10相互作用, 直接调控促生长转录因子的表达, 负调控蓝光信号转导途径。此外, TZP与phyB相互作用, 通过诱导FT和CO基因的表达, 参与phyB介导的开花调控过程。在远红光下, TZP与远红光受体phyA相互作用, 调控phyA在体内的蛋白磷酸化, 还通过抑制COP1与HY5的相互作用促进HY5蛋白的积累。实线箭头表示促进作用, 虚线箭头表示间接促进作用, T型箭头表示抑制作用。

Figure 2 Regulatory functions of TANDEM ZINC-FINGER/PLUS3 (TZP) in light signaling In blue light, TZP negatively regulates blue light signaling by physically interacting with ZFHD10 and directly modulating the expression of growth-promoting transcriptional regulators. In addition, TZP directly interacts with phyB and modulates phyB- dependent regulation of flowering by inducing the expression of FT and CO. In far-red light, TZP not only interacts with receptor phyA and regulates phyA phosphorylation in vivo, but also promotes HY5 protein abundance by competing for binding to COP1 as another substrate. The solid arrows represent direct promotion, the dotted arrow represents indirect promotion, the T-shaped arrows represent inhibition.

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植物光信号途径重要新调控因子TZP的研究进展

Research Progress on TZP, a Novel Key Regulator of Light Signal Transduction in Plants

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