植物SWEET基因参与逆境胁迫响应及其调控机制

doi:10.11983/CBB24158

植物学报 ›› 2025, Vol. 60 ›› Issue (4): 640-655.DOI: 10.11983/CBB24158 cstr: 32102.14.CBB24158

植物SWEET基因参与逆境胁迫响应及其调控机制

王鸿梅, 袁蔚, 薛芳, 张召聪, 刘坤, 陈四龙^*()

河北科技大学食品与生物学院, 石家庄 050018

收稿日期:2024-10-18 接受日期:2025-01-20 出版日期:2025-07-10 发布日期:2025-01-21
通讯作者: *陈四龙, 河北科技大学食品与生物学院研究员, 硕士生导师, 《中国油料作物学报》和Oil Crop Science期刊编委。主要从事花生等作物的分子育种、种质资源创新与评价、重要性状形成及调控机理研究。先后主持国家自然科学基金、河北省自然科学基金、河北省重点研发计划、河北省应用基础研究计划重点基础研究和河北省高层次人才资助项目等11项。发表学术论文40余篇, 其中SCI论文11篇, EI论文2篇。授权国家发明专利3项。参与制定地方标准和行业标准4项。获登记作物新品种3个。获省部级科技奖励一等奖5项、二等奖2项。E-mail: CHSL99@163.com
基金资助:
国家自然科学基金(32272097);国家自然科学基金(31771843);石家庄市科技计划(241490252A);河北省重点研发计划(21326332D)

The Functions of Plant SWEET Transporters and Their Regulatory Mechanisms in Stress Responses

Hongmei Wang, Wei Yuan, Fang Xue, Zhaocong Zhang, Kun Liu, Silong Chen^*()

College of Food Science and Biology, Hebei University of Science and Technology, Shijiazhuang 050018, China

Received:2024-10-18 Accepted:2025-01-20 Online:2025-07-10 Published:2025-01-21
Contact: *E-mail: CHSL99@163.com

摘要/Abstract

摘要： SWEETs是一类新发现的双向糖转运蛋白, 其家族成员在各种生物体中广泛存在。在植物中, 不同进化分支的SWEETs成员对转运已糖(葡萄糖、果糖和半乳糖)和蔗糖具有特异性, 通过特定的糖信号转导对生长发育和生理过程产生影响。该文重点综述了SWEETs转运蛋白响应生物和非生物胁迫的功能, 系统总结了SWEETs在转录水平、蛋白翻译后水平以及多种信号转导途径中响应环境胁迫的调控机制, 旨在为揭示SWEET转运蛋白的复杂生物学功能及其作用机制提供新的视角, 为未来植物抗逆研究和高产抗病作物分子育种提供有价值的参考。

关键词: 糖转运, SWEET, 胁迫响应, 调控机制

Abstract: SWEETs are a recently discovered family of bidirectional sugar transporters that are widely present in all organisms. Their high substrate specificity for hexoses (such as glucose, fructose and galactose) and sucrose in different clades underlines their significance in regulating sugar signaling during various developmental and physiological processes in plants. This review primarily focuses on how SWEETs precisely respond to various biotic and abiotic stresses. We summarized systematically the regulatory mechanisms of SWEETs in response to environmental stresses at both the transcriptional level and the post-translational level and in multiple signal transduction pathways. This review aims to provide a novel perspective and deeper understanding of the complex biological functions and regulating mechanisms of SWEET transporters, and provides valuable information for future research on plant stress resistance and molecular breeding crops with high yield and disease resistance.

Key words: sugar transport, SWEET, stress response, regulating mechanism

王鸿梅, 袁蔚, 薛芳, 张召聪, 刘坤, 陈四龙. 植物SWEET基因参与逆境胁迫响应及其调控机制. 植物学报, 2025, 60(4): 640-655.

Hongmei Wang, Wei Yuan, Fang Xue, Zhaocong Zhang, Kun Liu, Silong Chen. The Functions of Plant SWEET Transporters and Their Regulatory Mechanisms in Stress Responses. Chinese Bulletin of Botany, 2025, 60(4): 640-655.

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链接本文: https://www.chinbullbotany.com/CN/10.11983/CBB24158

https://www.chinbullbotany.com/CN/Y2025/V60/I4/640

图/表 4

图1 植物SWEET蛋白的跨膜结构(以花生AhSWEET12为例) THB1, 2: 三螺旋束串联结构; TM1-7: 跨膜α-螺旋结构域。带颜色的氨基酸残基为糖识别和结合关键位点。

Figure 1 Transmembrane structure of plant SWEET (take peanut AhSWEET12 as an example) THB1, 2: Triple-helix bundles; TM1-7: α-helical transmembrane domains. Amino acid residues are color-coded to highlight sites that play a critical role in the recognition and binding of sugar substrates.

图2 基于SWISS-MODEL (https://swissmodel.expasy.org/interactive)构建的植物SWEET蛋白三级结构(以花生AhSWEET12为例) TM1-7: 跨膜α-螺旋结构域。灰色阴影(点)为细胞膜。

Figure 2 The three-dimensional structure of plant SWEET protein (take peanut AhSWEET12 as an example) constructed with SWISS-MODEL (https://swissmodel.expasy.org/interactive) TM1-7: α-helical transmembrane domains. The grey shadow (spot) represent membrane.

图3 基于MEGA12 (beta)软件的邻接法构建拟南芥(At)、花生(Ah)和大豆(Gm) SWEET蛋白系统发育树

Figure 3 A phylogenetic tree of SWEET proteins from Arabidopsis thaliana (At), Arachis hypogaea (Ah) and Glycine max (Gm) based neighbor-joining method of MEGA12 (beta) software

图4 植物SWEET转运蛋白参与逆境胁迫响应的调控网络 TF: 转录因子; TALE: 转录激活因子类效应因子; SWEET: 糖转运蛋白; STP: 糖转运蛋白; CWIN: 细胞壁蔗糖转化酶; Sugar: 可溶性糖; Fru: 果糖; Glu: 葡萄糖; Suc: 蔗糖; EBE: 效应蛋白结合元件; Promoter: 基因启动子; IAA: 生长素; CTK: 细胞分裂素; ETH: 乙烯; GA: 赤霉素; ABA: 脱落酸; SnRK: 蔗糖非发酵-1-相关蛋白激酶; Ub: 泛素; P: 磷酸化

Figure 4 The regulatory network of plant SWEET transporters in response to various stresses TF: Transcription factor; TALE: Transcription activator-like effector; SWEET: Sugars will eventually be exported transporters; STP: Sugar transport proteins; CWIN: Sucrose invertase of cell wall; Sugar: Soluble sugars; Fru: Fructose; Glu: Glucose; Suc: Sucrose; EBE: Effector-binding element; Promoter: Gene promoter; IAA: Auxin; CTK: Cytokinin; ETH: Ethylene; GA: Gibberellin; ABA: Abscisic acid; SnRK: Sucrose non-fermenting-1-related protein kinase; Ub: Ubiquitin; P: Phosphorylation

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植物SWEET基因参与逆境胁迫响应及其调控机制

The Functions of Plant SWEET Transporters and Their Regulatory Mechanisms in Stress Responses

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