Expansion of the Molecular Network Related to Petal Development Based on MADS-box Proteins and Protein-Protein Interaction Network in Arabidopsis thaliana

doi:10.11983/CBB14169

Abstract

Abstract: The regulatory mechanism of flower organ development has an important role in evolution, development and ecology. Here, we used petal development of Arabidopsis thaliana as an example and integrated protein-protein interaction, subcellular localization, gene-chip and gene functional annotation databases to reveal a protein-protein interaction network related to petals of A. thaliana and built a reliable predictive model of protein-protein interaction. By using proteins containing the MADS-box domain as bait, we could expand the network by one level and obtained an expanded network of 38 proteins and 67 protein-protein interactions. Gene functional annotation with the DAVID database suggested that most of the proteins were involved in regulation of flower development in the expanded network. We derived 19 candidate tetrameric interactions, involving 8 genes, from the expanded network. None of the 8 genes belonged to the ABCDE model genes: AGL16, with an MADS-box domain, may be a new member or a redundant gene of class B. SEU, LUH, CHR4, CHR11, CHR17, and AT3G04960 were candidate targets of petal AP1-AP3-PI-SEP tetramers of A. thaliana. The results provide references for deeply analyzing the molecular regulatory network related to petal development of A. thaliana.

Key words: Arabidopsis thaliana, MADS-box, petal development, protein-protein interaction

CLC Number:

Q945.4

Li Yang, Congwei Sun, Zhijun Dai, Miao He, Zheming Yuan. Expansion of the Molecular Network Related to Petal Development Based on MADS-box Proteins and Protein-Protein Interaction Network in Arabidopsis thaliana[J]. Chinese Bulletin of Botany, 2015, 50(5): 614-622.

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URL: https://www.chinbullbotany.com/EN/10.11983/CBB14169

https://www.chinbullbotany.com/EN/Y2015/V50/I5/614

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