The Host Controls the Protein Level of Insect Effectors to Balance Immunity and Growth

doi:10.11983/CBB23064

Abstract

Abstract: Crop production is constantly threatened by various insect pests, revealing the mechanism underlying insect and host interaction is essential for environmentally-friendly pest management. Guangcun He and colleagues from Wuhan University identified and characterized a saliva protein BISP of the brown planthopper (BPH). In susceptible varieties, BISP targets OsRLCK185 and inhibits the basic defense. In varieties carrying the brown planthopper resistance gene Bph14, BPH14 directly binds to BISP and activates the host immune response but inhibits rice growth. BISP-BPH14 binds to the autophagic cargo receptor OsNBR1 and results in the degradation of BISP through the autophagic pathway, downregulating rice resistance against BPH and restoring the plant growth. This study illustrated the first insect salivary protein perceived by plant immune receptor, and revealed the molecular mechanism underlying the balance of immunity and growth in host by perceiving and regulating the protein level of insect effectors, which provides new ideas for developing high-yield insect resistant rice varieties.

Key words: rice, brown planthopper, insect resistance gene, saliva protein, autophagy

Yuqiang Liu, Jianmin Wan. The Host Controls the Protein Level of Insect Effectors to Balance Immunity and Growth[J]. Chinese Bulletin of Botany, 2023, 58(3): 353-355.

Add to citation manager EndNote|Ris|BibTeX

URL: https://www.chinbullbotany.com/EN/10.11983/CBB23064

https://www.chinbullbotany.com/EN/Y2023/V58/I3/353

Figures/Tables 1

References 9

[1]	Cruz AP, Arida A, Heong KL, Horgan FG (2011). Aspects of brown planthopper adaptation to resistant rice varieties with the Bph3 gene. Entomol Exp Appl 141, 245-257. DOI URL
[2]	Du B, Zhang WL, Liu BF, Hu J, Wei Z, Shi ZY, He RF, Zhu LL, Chen RZ, Han B, He GC (2009). Identification and characterization of Bph14, a gene conferring resistance to brown planthopper in rice. Proc Natl Acad Sci USA 106, 22163-22168. DOI URL
[3]	Dyck VA, Thomas B (1979). The brown planthopper pro-blem. In: Brady NC, ed. Brown Planthopper:Threat to Rice Production in Asia. Los Baños: International Rice Research Institute. pp. 3-17.
[4]	Guo JP, Wang HY, Guan W, Guo Q, Wang J, Yang J, Peng YX, Shan JH, Gao MY, Shi SJ, Shangguan XX, Liu BF, Jing SG, Zhang J, Xu CX, Huang J, Rao WW, Zheng XH, Wu D, Zhou C, Du B, Chen RZ, Zhu LL, Zhu YX, Walling LD, Zhang QF, He GC (2023). A tripartite rheostat controls self-regulated host plant resistance to insect. Nature 618, 799-807. DOI
[5]	Hu L, Wu Y, Wu D, Rao WW, Guo JP, Ma YH, Wang ZZ, Shangguan XX, Wang HY, Xu CX, Huang J, Shi SJ, Chen RZ, Du B, Zhu LL, He GC (2017). The coiled-coil and nucleotide binding domains of BROWN PLANTHOPPER RESISTANCE 14 function in signaling and resistance against planthopper in rice. Plant Cell 29, 3157-3185. DOI URL
[6]	Huang HJ, Wang YZ, Li LL, Lu HB, Lu JB, Wang X, Ye ZX, Zhang ZL, He YJ, Lu G, Zhuo JC, Mao QZ, Sun ZT, Chen JP, Li JM, Zhang CX (2023). Planthopper salivary sheath protein LsSP1 contributes to manipulation of rice plant defenses. Nat Commun 14, 737. DOI
[7]	Lolle S, Stevens D, Coaker G (2020). Plant NLR-triggered immunity: from receptor activation to downstream signa-ling. Curr Opin Immunol 62, 99-105. DOI URL
[8]	Rossi M, Goggin FL, Milligan SB, Kaloshian I, Ullman DE, Williamson VM (1998). The nematode resistance gene Mi of tomato confers resistance against the potato aphid. Proc Natl Acad Sci USA 95, 9750-9754. DOI PMID
[9]	Zhao Y, Huang J, Wang ZZ, Jing SL, Wang Y, Ouyang YD, Cai BD, Xin XF, Liu X, Zhang CX, Pan YF, Ma R, Li QF, Jiang WH, Zeng Y, Shangguan XX, Wang HY, Du B, Zhu LL, Xu X, Feng YQ, He SY, Chen RZ, Zhang QF, He GC (2016). Allelic diversity in an NLR gene BPH9 enables rice to combat planthopper variation. Proc Natl Acad Sci USA 113, 12850-12855. DOI PMID

[1]	Juan Cui, Xiaoyu Yu, Yuejiao Yu, Chengwei Liang, Jian Sun, Wenfu Chen. Analysis of Texture Factors and Genetic Basis Influencing the Differences in Eating Quality between Northeast China and Japanese Japonica Rice [J]. Chinese Bulletin of Botany, 2025, 60(4): 1-0.
[2]	Zhao Ling, Guan Ju, Liang Wenhua, Zhang Yong, Lu Kai, Zhao Chunfang, Li Yusheng, Zhang Yadong. Mapping of QTLs for Heat Tolerance at the Seedling Stage in Rice Based on a High-density Bin Map [J]. Chinese Bulletin of Botany, 2025, 60(3): 342-353.
[3]	Xinyu Li, Yue Gu, Feifei Xu, Jinsong Bao. Research Progress on Post-translational Modifications of Starch Biosynthesis-related Proteins in Rice Endosperm [J]. Chinese Bulletin of Botany, 2025, 60(2): 256-270.
[4]	Jianguo Li, Yi Zhang, Wenjun Zhang. Iron Plaque Formation and Its Effects on Phosphorus Absorption in Rice Roots [J]. Chinese Bulletin of Botany, 2025, 60(1): 132-143.
[5]	Ruifeng Yao, Daoxin Xie. Activation and Termination of Strigolactone Signal Perception in Rice [J]. Chinese Bulletin of Botany, 2024, 59(6): 873-877.
[6]	Jinjin Lian, Luyao Tang, Yinuo Zhang, Jiaxing Zheng, Chaoyu Zhu, Yuhan Ye, Yuexing Wang, Wennan Shang, Zhenghao Fu, Xinxuan Xu, Richeng Wu, Mei Lu, Changchun Wang, Yuchun Rao. Genetic Locus Mining and Candidate Gene Analysis of Antioxidant Traits in Rice [J]. Chinese Bulletin of Botany, 2024, 59(5): 738-751.
[7]	Jiahui Huang, Huimin Yang, Xinyu Chen, Chaoyu Zhu, Yanan Jiang, Chengxiang Hu, Jinjin Lian, Tao Lu, Mei Lu, Weilin Zhang, Yuchun Rao. Response Mechanism of Rice Mutant pe-1 to Low Light Stress [J]. Chinese Bulletin of Botany, 2024, 59(4): 574-584.
[8]	Jianmin Zhou. A Combat Vehicle with a Smart Brake [J]. Chinese Bulletin of Botany, 2024, 59(3): 343-346.
[9]	Chaoyu Zhu, Chengxiang Hu, Zhenan Zhu, Zhining Zhang, Lihai Wang, Jun Chen, Sanfeng Li, Jinjin Lian, Luyao Tang, Qianqian Zhong, Wenjing Yin, Yuexing Wang, Yuchun Rao. Mapping of QTLs Associated with Rice Panicle Traits and Candidate Gene Analysis [J]. Chinese Bulletin of Botany, 2024, 59(2): 217-230.
[10]	Bao Zhu, Jiangzhe Zhao, Kewei Zhang, Peng Huang. OsCKX9 is Involved in Regulating the Rice Lamina Joint Development and Leaf Angle [J]. Chinese Bulletin of Botany, 2024, 59(1): 10-21.
[11]	Yanli Fang, Chuanyu Tian, Ruyi Su, Yapei Liu, Chunlian Wang, Xifeng Chen, Wei Guo, Zhiyuan Ji. Mining and Preliminary Mapping of Rice Resistance Genes Against Bacterial Leaf Streak [J]. Chinese Bulletin of Botany, 2024, 59(1): 1-9.
[12]	Tian Chuanyu, Fang Yanli, Shen Qing, Wang Hongjie, Chen Xifeng, Guo Wei, Zhao Kaijun, Wang Chunlian, Ji Zhiyuan. Genotypic Diversity and Pathogenisity of Xanthomonas oryzae pv. oryzae Isolated from Southern China in 2019-2021 [J]. Chinese Bulletin of Botany, 2023, 58(5): 743-749.
[13]	Dai Ruohui, Qian Xinyu, Sun Jinglei, Lu Tao, Jia Qiwei, Lu Tianqi, Lu Mei, Rao Yuchun. Research Progress on the Mechanisms of Leaf Color Regulation and Related Genes in Rice [J]. Chinese Bulletin of Botany, 2023, 58(5): 799-812.
[14]	Jiayi Jin, Yiting Luo, Huimin Yang, Tao Lu, Hanfei Ye, Jiyi Xie, Kexin Wang, Qianyu Chen, Yuan Fang, Yuexing Wang, Yuchun Rao. QTL Mapping and Expression Analysis on Candidate Genes Related to Chlorophyll Content in Rice [J]. Chinese Bulletin of Botany, 2023, 58(3): 394-403.
[15]	Shang Sun, Yingying Hu, Yangshuo Han, Chao Xue, Zhiyun Gong. Double-stranded Labelled Oligo-FISH in Rice Chromosomes [J]. Chinese Bulletin of Botany, 2023, 58(3): 433-439.