植物学报 ›› 2019, Vol. 54 ›› Issue (1): 81-92.DOI: 10.11983/CBB18012

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活性氧调控植物细胞自噬的研究进展

马丹颖,季东超,徐勇,陈彤(),田世平   

  1. 中国科学院植物研究所, 中国科学院北方资源植物重点实验室, 北京 100093
  • 收稿日期:2018-01-12 接受日期:2018-03-13 出版日期:2019-01-30 发布日期:2019-07-31
  • 通讯作者: 陈彤
  • 基金资助:
    国家科技支撑计划(2015BAD16B01-3);国家自然科学基金(31530057, No.31672210, No.31670183)

Advances in the Regulation on Autophagy by Reactive Oxygen Species in Plant Cells

Danying Ma,Dongchao Ji,Yong Xu,Tong Chen(),Shiping Tian   

  1. Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
  • Received:2018-01-12 Accepted:2018-03-13 Online:2019-01-30 Published:2019-07-31
  • Contact: Tong Chen

摘要:

真核生物通过双层膜结构包裹细胞内受损的蛋白、细胞器或外源物质, 经溶酶体(或液泡)将内含物降解并进行循环利用, 这种高度保守的生物学过程称为自噬。活性氧是细胞有氧代谢的副产物, 作为一种信号分子广泛参与不同生物学过程的调控。研究表明, 真核生物中自噬与活性氧之间存在密切联系。该文结合近年的研究进展, 对植物细胞中活性氧的种类及作用和自噬的分子机制等进行概述, 旨在探讨活性氧对自噬的调控作用。

关键词: 自噬, 活性氧, 调控

Abstract:

Damaged proteins, organelles or exogenous substances are engulfed in double membrane vesicles and delivered to the lysosome (vacuoles) for degradation and recycled in eukaryotes. This highly conserved biological process is called autophagy. Reactive oxygen species (ROS) are byproducts of cellular aerobic metabolism, which are widely involved in the regulating different biological processes as signaling molecules. Recent evidence suggests a strong link between autophagy and ROS in plants. Here, we summarize the types and roles of ROS and describe the molecular mechanism of autophagy according to the latest research in plants. The effect of ROS on regulation of autophagy is mainly discussed.

Key words: autophagy, reactive oxygen species, regulation