成花素FT：环境感知与发育调控的信号枢纽

doi:10.11983/CBB25203

摘要/Abstract

摘要： FT (FLOWERING LOCUS T)是一种由叶片合成并可向顶端分生组织移动的信号蛋白, 作为成花素在开花诱导与发育转变中发挥核心作用。近年来, 围绕FT合成、运输以及成花素激活复合体(FAC)的组装和调控机制等方面的研究取得了重要进展, 为理解植物发育调控网络奠定了坚实基础。近日, 一项最新研究整合了蛋白-DNA互作、液-液相分离及发育时空表达等多重调控机制, 将传统的静态FAC模型拓展为动态、多层次的组装模型, 为理解植物如何整合环境信号以调控生殖发育提供了新的分子视角。鉴于此, 本文系统梳理了有关FT与FAC的研究进展和当前亟待解决的关键问题, 并展望了未来的发展方向, 以期为深入解析植物发育调控机制以及作物育种应用提供新思路。

关键词: 成花素FT, 成花素激活复合体, 开花时间, 植物发育调控

Abstract: FLOWERING LOCUS T (FT) is a signaling protein synthesized in leaves and transported to the shoot apical meristem, where it functions as florigen, a key inducer of flowering and developmental transitions. Substantial progress has been made in elucidating the mechanisms underlying FT synthesis, transport, and the assembly and regulation of the florigen activation complex (FAC), providing a solid foundation for understanding plant developmental regulatory networks. Recently, a study integrated multiple regulatory layers, including protein-DNA interactions, liquid-liquid phase separation, and spatiotemporal expression patterns, thereby extending the traditional static FAC model into a dynamic and multilayered assembly framework. This work offers new molecular insights into how plants integrate environmental cues to regulate reproductive development. In this review, we summarize recent advances in FT and FAC research, highlight key outstanding questions, and discuss future directions, aiming to provide fresh perspectives for elucidating plant developmental regulation and for potential applications in crop improvement.

Key words: florigen FT, florigen activation complex (FAC), flowering time, plant developmental regulation

牛钰凡, 陈玲玲, 苏晨, 王雷. 成花素FT：环境感知与发育调控的信号枢纽. 植物学报, DOI: 10.11983/CBB25203.

Yufan Niu, Lingling Chen, Chen Su, Lei Wang. Florigen FT: A Signaling Hub Connecting Environmental Cues and Developmental Regulation. Chinese Bulletin of Botany, DOI: 10.11983/CBB25203.

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