Chinese Bulletin of Botany ›› 2020, Vol. 55 ›› Issue (5): 533-536.DOI: 10.11983/CBB20158

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Antifungal Compounds Come in Handy

Jian-Min Zhou1,*(), Lidong Cao2   

  1. 1College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, State Key Laboratory of Plant Genomics, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
    2Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China
  • Received:2020-09-15 Accepted:2020-09-18 Online:2020-09-01 Published:2020-09-21
  • Contact: Jian-Min Zhou


Pathogenic microbes employ specialized mechanisms to breach defense of host plants, causing diseases on plants and losses in agricultural production. Understanding mechanisms of pathogenesis offers new avenues for disease control. A team from Sichuan Agriculture University led by Xuewei Chen investigated mechanisms underlying the genera- tion of an infection structure called penetration peg, which is employed by many fungal pathogens such as the one causing blast disease on rice. They discovered that very-long-chain fatty acids are required for this process. They further demonstrated that a group of commercialized herbicides capable of inhibiting very-long-chain fatty acid biosynthesis in fungi can effectively inhibit pathogenesis of a broad spectrum of fungi, which brings new technology to control diseases and provides new ideas for new pesticides discovery.

Key words: rice blast, penetration peg, rice, pesticide, very-long-chain fatty acids