植物学报 ›› 2016, Vol. 51 ›› Issue (1): 130-143.DOI: 10.11983/CBB14216

• 专题论坛 • 上一篇    

亚硝基化在植物细胞死亡及防御反应中的作用

刘振, 刘霞, 刘建中*()   

  1. 浙江师范大学化学与生命科学学院, 金华 321004
  • 收稿日期:2014-12-25 接受日期:2015-03-30 出版日期:2016-01-01 发布日期:2016-02-01
  • 通讯作者: 刘建中
  • 作者简介:? 共同第一作者
  • 基金资助:
    基金项目: 国家自然科学基金(No.31371407)、浙江省钱江人才计划(No.2013R10074)、人力资源和社会保障部留学人员择优资助项目(No;ZC304013131)和浙江省自然科学基金(No;LY12C14001)

The Roles of Protein S-nitrosylation in Plant Cell Death and Disease Resistance

Zhen Liu, Xia Liu, Jianzhong Liu*   

  1. College of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China
  • Received:2014-12-25 Accepted:2015-03-30 Online:2016-01-01 Published:2016-02-01
  • Contact: Liu Jianzhong
  • About author:? These authors contributed equally to this paper

摘要:

亚硝基化是近年来新发现的不依赖于环磷酸鸟苷的一氧化氮信号转导途径, 是一氧化氮分子通过共价结合修饰靶蛋白的半胱氨酸残基从而改变其功能的过程。该文重点综述了近年来亚硝基化在细胞死亡和抗病反应这两个紧密关联的生物学过程中的最新研究成果, 总结了亚硝基化通过修饰和调控靶蛋白从而促进或抑制细胞死亡和抗病反应, 并对现有研究结果中某些不一致之处提出自己的观点。最后根据动物学领域的最新研究进展对植物学领域未来亚硝基化的研究方向进行了展望。

关键词: 细胞死亡, 抗病性, 一氧化氮, 亚硝基谷胱甘肽还原酶, 亚硝基化

Abstract:

S-nitrosylation, a newly identified cGMP-independent nitric oxide (NO) signaling pathway, is a post- translational modification in which NO moiety is covalently attached to the cysteine thiol group of a target protein, thereby leading to functional changes of modified proteins. Here, we review the recent progress in understanding the roles of S-nitrosylation in plant cell death and disease resistance, two closely interconnected biological processes. We summarize how NO promotes or inhibits cell death and disease resistance though S-nitrosylation of key proteins that participate in certain biological processes. We also give our comments on the inconsistent results regarding the role of S-nitrosylation in cell death and disease resistance from different groups. From the most recent progress made in animal systems, we provide perspectives for plant biologists in this field.

Key words: cell death, disease resistance, nitric oxide, S-nitrosogluta thionereductase (GSNOR1), S-nitrosylation