关键词: PPR蛋白,  RNA C→U编辑,  线粒体,  叶绿体

Abstract: Mitochondria and chloroplasts harboring themselves genomes are semi-autonomous organelles. Post-transcriptional processing is essential for the expression of organelle genes, one of which is RNA C→U editing. Multiple editing factors were reported to involve in RNA C→U editing. The PPR-motifs array in PPR proteins specifically target editing sites, and the DYW domains in PPR-DYW proteins catalyze the deaminase in the cytidine (C)-to-uridine (U) editing. This paper aims to review the recent advance which PPR proteins involve in RNA C→U editing, and the potential application value of synthetic PPR editing factors.

Key words: PPR proteins,  RNA C→U editing,   mitochondria,   chloroplasts