模式识别受体的胞内转运及其在植物免疫中的作用

doi:10.11983/CBB19139

摘要/Abstract

摘要： 植物利用细胞表面模式识别受体(PRRs)来感知病原相关分子模式(PAMPs), 进而触发自身的免疫反应(PTI)。在植物免疫过程中, PRRs在细胞内的正确定位对其生理功能的发挥至关重要。PRRs蛋白可以在内质网(ER)上合成, 并通过胞吐被分泌到质膜(PM)上。此外, PRRs蛋白也可以通过胞吞进行胞内循环或降解。细胞可以通过胞内转运降解PRRs蛋白以终止信号转导, 也可以通过形成胞内体进行信号传递。该文概述了PRRs蛋白及其配体的研究进展以及PRRs蛋白的胞内转运在植物免疫中的重要作用。

关键词: 模式识别受体(PRRs), 病原相关分子模式(PAMPs), 胞内转运, 病原相关分子模式触发的免疫(PTI), 植物免疫

Abstract: Plants initially sense microbes via perception of pathogen associated molecular patterns (PAMPs) by pattern-recognition receptors (PRRs) located on the cell surface. This recognition is referred to as PAMP-triggered immunity (PTI). In order to ensure their physiological and cellular functions, PRRs must be properly conveyed from their site of synthesis, i.e., the endoplasmic reticulum, to their final destination, the plasma membrane (PM), through the secretory pathway. PRRs also rely on recycling and/or degradation, two processes that are initiated by endocytosis. Intracellular trafficking serves to terminate signaling through degradation, sustains signaling through recycling, or relays signaling inside the cell through the formation of signaling endosomes. In this review, we summarize the current knowledge of plant PRRs and their ligands, illustrating that intracellular trafficking plays an important role in plant immunity.

Key words: pattern recognition receptors (PRRs), pathogen-associated molecular patterns (PAMPs), intracellular traffic-king, PRR-triggered immunity (PTI), plant immunity

崔亚宁, 钱虹萍, 赵艳霞, 李晓娟. 模式识别受体的胞内转运及其在植物免疫中的作用. 植物学报, 2020, 55(3): 329-339.

Yaning Cui, Hongping Qian, Yanxia Zhao, Xiaojuan Li. Intracellular Trafficking in Pattern Recognition Receptor-triggered Plant Immunity. Chinese Bulletin of Botany, 2020, 55(3): 329-339.

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链接本文: https://www.chinbullbotany.com/CN/10.11983/CBB19139

https://www.chinbullbotany.com/CN/Y2020/V55/I3/329

图/表 4

图1 植物模式识别受体及其信号分子

Figure 1 Plant pattern recognition receptors and their signaling adapters

图2 以FLS2为例图示细胞表面防卫反应

Figure 2 A model of FLS2-mediated defense at the cell surface

图3 FLS2蛋白胞吞转运模式

Figure 3 Schematic overview of FLS2 endocytosis

图4 模式识别受体(PRRs)蛋白分泌途径

Figure 4 Pattern recognition receptors (PRRs) trafficking in the endomembrane system

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