植物学报 ›› 2016, Vol. 51 ›› Issue (2): 274-280.DOI: 10.11983/CBB15072 cstr: 32102.14.CBB15072
• 专题论坛 • 上一篇
收稿日期:
2015-04-20
接受日期:
2015-09-08
出版日期:
2016-03-01
发布日期:
2016-03-31
通讯作者:
E-mail: 基金资助:
Linya Liu, Yacheng Huang, Xiaolong Huang, Dongyi Huang*()
Received:
2015-04-20
Accepted:
2015-09-08
Online:
2016-03-01
Published:
2016-03-31
Contact:
E-mail: 摘要: Dioscorin是薯蓣(Dioscorea spp.)植物块茎中主要的贮藏蛋白, 具有块茎特异性表达的特点。研究证实它不仅有一般贮藏蛋白的特性, 该特性可能与薯蓣块茎的形成过程密切相关; 而且还有碳酸酐酶、胰蛋白酶抑制剂、抗氧化、抗高血压以及免疫调节的活性, 故薯蓣植物具有开发成功能性食品和蛋白质类医药的潜力。该文就近年来对其块茎特异蛋白的结构特征、性质和功能以及在分子生物学水平上的研究进展进行了综述。
刘林娅, 黄亚成, 黄小龙, 黄东益. 薯蓣植物块茎特异蛋白Dioscorin的研究进展. 植物学报, 2016, 51(2): 274-280.
Linya Liu, Yacheng Huang, Xiaolong Huang, Dongyi Huang. Advances in Study of Dioscorins as Special Proteins in Yam Tuber. Chinese Bulletin of Botany, 2016, 51(2): 274-280.
[1] | 程文杰 (2010). 大薯种质资源遗传多样性分析. 硕士论文. 海口: 海南大学. |
[2] | 邓秋红, 甘露, 付春华, 栗茂藤, 余龙江 (2009). 芸臺属中几个物种碳酸酐酶活性的比较. 植物生理学通讯 45, 663-666. |
[3] | 甘立军, 曾晓春, 周燮 (2001). 茉莉酸类与植物地下贮藏器官的形成. 植物学通报 18, 546-553. |
[4] | 李建喜, 杨志强, 王学智 (2006). 活性氧自由基在动物机体内的生物学作用. 动物医学进展 27(10), 33-36. |
[5] | 李胜利 (2004). 营养与膳食. 北京: 人民卫生出版社. |
[6] | 苗明三 (2002). 氧自由基、疾病与抗氧化中药. 河南中医药学刊 17(4), 1-4. |
[7] | 辛志宏, 马海乐, 吴守一 (2003). 食品蛋白质中血管紧张素转化酶抑制肽的研究. 江苏大学学报(自然科学版) 24(4),17-21. |
[8] | 赵玉国, 吴沿友 (2009). 光质对组培苗叶绿素含量和碳酸酐酶活性及生长的影响. 现代农业科学 4, 16-18. |
[9] | 周双清, 胡新文, 黄东益, 黄小龙 (2011). 参薯组织培养的初步研究. 中国热带农业 5, 85-87. |
[10] |
周晓薇, 王静, 段浩, 顾镍, 刘红彦, 曾晓雄 (2011). 铁棍山药蛋白质的分离纯化及体外抗氧化活性. 食品科学 32(9), 31-35.
DOI |
[11] | Akanbi CT, Gureje PO, Adeyemi IA (1996). Effect of heat-moisture pre-treatment on physical characteristics of dehydrated yam. J Food Eng 28, 45-54. |
[12] | Araghinknam M, Chung S, White TN, Eskelson E, Waston RR (1996). Antioxidant activity of dioscorea and dehydroepiandrosterone (DHEA) in older humans. Life Sci 59, PL147-PL157. |
[13] | Balestrazzi A, Gonfalonieri M, Odoardi M, Ressegotti V, Allegro G, Tava A, Carbonera D (2004). A trypsin inhibitor cDNA from a novel source, snail medic (Medicago scutellata L.): cloning and functional expression in response to wounding, herbivore, jasmonic and salicylic acid. Plant Sci 167, 337-346. |
[14] |
Boulter D, Gatehouse AM, Hilder V (1989). Use of cowpea trypsin inhibitor (CpTI) to protect plants against insect predation. Biotechnol Adv 7, 489-497.
PMID |
[15] |
Conlan RS, Griffiths LA, Napier JA, Shewry PR, Mantell S, Ainsworth C (1995). Isolation and characterisation of cDNA clones representing the genes encoding the major tuber storage protein (dioscorin) of yam (Dioscorea cayenensis Lam.). Plant Mol Biol 28, 369-380.
PMID |
[16] | Conlan S, Griffiths LA, Turner M, Fido R, Tatham A, Ainsworth C, Shewry P (1998). Characterisation of the yam tuber storage protein dioscorin. J Plant Physiol 153, 25-31. |
[17] | Drazkiewicz M, Skorzynska-Polit E, Krupa Z (2010). Effect of BSO-supplemented heavy metals on antioxidant enzymes in Arabidopsis thaliana. Ecotoxicol Environ Saf 73, 1362-1369. |
[18] |
Fu LS, Ko YH, Lin KW, Hsu JY, Chu JJ, Chi CS (2009). Dioscorin protects tight junction protein expression in A549 human airway epithelium cells from dust mite damage. J Microbiol Immunol Infect 42, 457-463.
PMID |
[19] | Fu SL, Hsu YH, Lee PY, Hou WC, Hung LC, Lin CH (2006). Dioscorin isolated from Dioscorea alata activates TLR4-signaling pathways and induces cytokine expression in macrophages. Biochem Biophys Res Commun 339, 137-144. |
[20] |
Gaidamashvili M, Ohizumi Y, Iijima S, Takayama T, Ogawa T, Muramoto K (2004). Characterization of the yam tuber storage proteins from Dioscorea batatas exhibiting unique lectin activities. J Biol Chem 279, 26028-26035.
DOI PMID |
[21] | Han CH, Lin YS, Lin SY, Hou WC (2014). Antioxidant and antiglycation activities of the synthesised dipeptide, Asn-Trp, derived from computer-aided simulation of yam dioscorin hydrolysis and its analogue, Gln-Trp. Food Chem 147, 195-202. |
[22] | Han CH, Liu JC, Fang SU, Hou WC (2013). Antioxidant activities of synthesised thiol-contained peptides derived from computer-aided pepsin hydrolysis of yam tuber storage protein, dioscorin. Food Chem 138, 923-930. |
[23] | Harvey PJ, Boulter D (1983). Isolation and characterization of the storage protein of yam tubers (Dioscorea rotundata). Phytochemistry 22, 1687-1693. |
[24] | Heweet-Emmett D, Tashian RE (1996). Functional diversity, conervation, and convergence in the evolution of the α-, β-, and γ-carbonic anhydrase gene families. Mol Phylogenet Evol 5, 50-77. |
[25] | Hou WC, Chen HJ, Lin YH (1999b). Dioscorin, the major tuber storage protein of yam (Dioscorea batatas Decne), with dehydroascorbate reductase and monodehydroas- corbate reductase activities. Plant Sci 149, 151-156. |
[26] | Hou WC, Chen HJ, Lin YH (2000). Dioscorins from different Dioscorea species all exhibit both carbonic anhydrase and trypsin inhibitor activities. Bot Bull Acad Sinica 41, 191-196. |
[27] | Hou WC, Lee MH, Chen HJ, Liang WL, Han CH, Liu YW, Lin YH (2001). Antioxidant activities of dioscorin, the storage protein of yam (Dioscorea batatas Decne). J Agric Food Chem 49, 4956-4960. |
[28] | Hou WC, Liu JS, Chen HJ, Chen TE, Chang CF, Lin YH (1999a). Dioscorin, the major tuber storage protein of yam (Dioscorea batatas Decne), with carbonic anhydrase and trypsin inhibitor activities. J Agric Food Chem 47, 2168-2172. |
[29] | Hsu FL, Lin YH, Lee MH, Lin CL, Hou WC (2002). Both dioscorin, the tuber storage protein of yam (Dioscorea alata cv. ‘Tainong No. 1’), and its peptic hydrolysates exhibited angiotensin converting enzyme inhibitory activities. J Agric Food Chem 50, 6109-6113. |
[30] | Hsu YJ, Weng CF, Lin KW, Lin KC (2013). Suppression of allergic reactions in ovalbumin-sensitized mice by yam storage proteins dioscorins. J Agric Food Chem 61, 11460-11467. |
[31] |
Koiwa H, Shade RE, Zhu-Salzman K, D’Urzo MP, Murdock LL, Bressan RA, Hasegawa PM (2000). A plant defensive cystatin (soyaeystatin) targets cathepsin L-Like digestive cysteine Proteinases (DvCALs) in the larval midgut of western corn rootworm (Diabrotica virgifera). FEBS Lett 471, 67-70.
DOI PMID |
[32] | Lawton JR, Lawton JRS (1967). The morphology of the dormant embryo and young seedling of five species of Dioscorea from Nigeria. Proceedings of the Linnean Society of London 178, 153-159. |
[33] | Li SC (1596). Pen Tsao Kang Mu (Systematic Pharmacopoeia). China, 1518-1593. |
[34] | Liao YH, Tseng CY, Chen W (2006). Structural characterization of dioscorin, the major tuber protein of yams, by near infrared Raman spectroscopy. J Phys Conf Ser 28, 119-122. |
[35] | Lin PL, Lin KW, Weng CF, Lin KC (2009). Yam storage protein dioscorins from Dioscorea alata and Dioscorea japonica exhibit distinct immunomodulatory activities in mice. J Agric Food Chem 57, 4606-4613. |
[36] | Liu YW, Liu JC, Huang CY, Wang CK, Shang HF, Hou WC (2009). Effects of oral administration of yam tuber storage protein, dioscorin, to BALB/c mice for 21-days on immune responses. J Agric Food Chem 57, 9274-9279. |
[37] | Liu YW, Shang HF, Wang CK, Hsu FL, Hou WC (2007). Immunomodulatory activity of dioscorin, the storage protein of yam (Dioscorea alata cv. ‘Tainong No. 1’) tuber. Food Chem Toxicol 45, 2312-2318. |
[38] | Nagai T, Nagashima T (2006). Functional properties of dioscorin, a soluble viscous protein from Japanese yam (Dioscorea opposita Thunb.) tuber mucilage tororo. Z Naturforsch C 61, 792-798. |
[39] | Omonigho SE, Ikenebomeh MJ (2000). Effect of temperature treatment on the chemical composition of pounded white yam during storage. Food Chem 71, 215-220. |
[40] | Racuseu D, Foote M (1980). A major soluble glycoprotein of potato tubers. J Food Biochem 4, 43-52. |
[41] |
Ryan CA (1989). Proteinase inhibitor gene families: strategies for transformation to improve plant defenses against herbivores. BioEssays 10, 20-24.
DOI PMID |
[42] | Shewry PR (2003). Tuber storage proteins. Ann Bot 91, 755-769. |
[43] | Tsai WY, Jheng YJ, Chen KH, Lin KW, Ho YP, Yang CC, Lin KC (2013). Molecular cloning, structural analysis and mass spectrometric identification of native dioscorins of various yam species. J Sci Food Agric 93, 761-770. |
[44] | Wanasundera JPD, Ravindran G (1994). Nutritional assessment of yam (Dioscorea lata) tubers. Plant Foods Hum Nutr 46, 33-39. |
[45] | Xue YL, Miyakawa T, Nakamura A, Hatano K, Sawano Y, Tanokura M (2015). Yam tuber storage protein reduces plant oxidants using the coupled reactions as carbonic anhydrase and dehydroascorbate reductase. Mol Plant 8, 1115-1118. |
[46] | Xue YL, Miyakawa T, Sawano Y, Tanokura M (2012a). Cloning of genes and enzymatic characterizations of no- vel dioscorin isoforms from Dioscorea japonica. Plant Sci 183, 14-19. |
[47] | Xue YL, Miyakawa T, Sawano Y, Tanokura M (2012b). Crystallization and preliminary X-ray crystallographic ana- lysis of dioscorin from Dioscorea japonica. Acta Crystallogr Sect F Struct Biol Cryst Commun 68, 193-195. |
[48] | Yang CC, Lin KC (2014). Class A dioscorins of various yam species suppress ovalbumin-induced allergic reactions. Immunopharmacol Immunotoxicol 36, 242-249. |
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