Research Advances in Functions of SUMO E3 Ligases in Plant Growth and Development

doi:10.11983/CBB17144

Abstract

Abstract: SUMOylation is an important type of protein posttranslational modification. SUMO E3 ligases are critical in this process via substrate recognition and reaction enhancement. Several SUMO E3 ligases, involved in development regulation, have been identified in plants. Here, we summarize the research advances in the functions of SUMO E3 ligases in root development, flowering, gametogenesis and photomorphogenesis and prospects for further study.

Key words: MMS21, plant growth and development, SIZ1, SUMO E3 ligases, SUMOylation

Han Danlu, Lai Jianbin, Yang Chengwei. Research Advances in Functions of SUMO E3 Ligases in Plant Growth and Development[J]. Chinese Bulletin of Botany, 2018, 53(2): 175-184.

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URL: https://www.chinbullbotany.com/EN/10.11983/CBB17144

https://www.chinbullbotany.com/EN/Y2018/V53/I2/175

Figures/Tables 2

Figure 1 The domains are conserved in plant SUMO E3 ligases(A) Characteristic domains of plant SUMO E3 ligases. MMS21 and SIZ1 are shown by boxes, SIZ1 possesses SAP, PHD, PINIT, SP-RING and SXS domains, while MMS21 possesses only SP-RING domain (Ishida et al., 2012); (B) A schematic model of the SP-RING domain of SUMO E3 ligases and the RING finger of ubiquitin E3 ligases. The RING domain sports two zinc-coordinating loops, the SP-RING domain contains only one, the second loop is instead held together by hydrogen bonds and Van der Waals forces (Duan et al., 2009; Yunus and Lima, 2009; Ishida et al., 2012); (C), (D) The sequence data for the plant SIZ1 homologues were obtained from the NCBI protein database. Sequence identities (black boxes) and similarities (gray boxes) of amino acids were identified by DNAMAN. Amino acid sequences of SIZ1 proteins are from Arabidopsis thaliana AtSIZ1 (AAU00414.1), Glycine max GmSIZ1a (KRH24918.1), GmSIZ1b (KRG89029.1), Oryza sativa OsSIZ1 (BAG97182.1), OsSIZ2 (BAG89374.1), and Zea mays ZmSIZ1a (AQK95338.1), ZmSIZ1b (AQK79048.1), ZmSIZc (ONM41936.1). Amino acid sequences of MMS21 proteins are from Arabidopsis thaliana AtMMS21 (NP_188133.2), Glycine max GmMMS21 (XP_003541835.1), Oryza sativa OsMMS21 (XP_015640264.1), and Zea mays ZmMMS21 (AQK88509.1).

Figure 2 The functions of SUMO E3 ligases in Arabidopsis(A) The function of MMS21 regulates in cell cycle (Liu et al., 2016); (B) MMS21 and SIZ1 are both involved in flowering pathway and time (Kwak et al., 2016); (C) MMS21 responses to the DNA damage to regulate plant growth and development (Xu et al., 2013; Yuan et al., 2014); (D) MMS21 is involved in Arabidopsis root development by auxin (Ishida et al., 2009; Huang et al., 2009; Zhang et al., 2010); (E) MMS21 is involved in root development by regulating chromatin remodeling complex (Zhang et al., 2017a); (F) SIZ1 regulate glucose metabolism germinated/seedling development (Miura et al., 2009); (G) SIZ1 is involved in flowering pathway (Jin et al., 2008); (H) SIZ1 regulates the photomorphogenesis (Kim et al., 2016a; Lin et al., 2016); (I) SIZ1 regulation of phosphate starvation-induced root architecture remodeling involves the control of auxin accumulation (Miura et al., 2005, 2011); (J) SIZ1 regulates development of root by sugar pathway (Castro et al., 2015)

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