Chinese Bulletin of Botany ›› 2023, Vol. 58 ›› Issue (6): 935-945.DOI: 10.11983/CBB23050

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Aptamers and Their Applications in Plant Science Researches

Yi Li1,2,3,, Xi Zhang1,2,3,, Yanhui Yuan1,2,3, Pichang Gong4,*(), Jinxing Lin1,2,3,*()   

  1. 1State Key Laboratory of Tree Genetics and Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China
    2College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083, China
    3Institute of Tree and Genome Editing, Beijing Forestry University, Beijing 100083, China
    4State Key Laboratory of Plant Diversity and Specialty Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
  • Received:2023-04-14 Accepted:2023-08-19 Online:2023-11-01 Published:2023-11-27
  • Contact: * E-mail: gongpeichang@ibcas.ac.cn;linjx@ibcas.ac.cn
  • About author: These authors contributed equally to this paper

Abstract: Aptamers are single-stranded oligonucleotides or short peptides that are screened and selected from artificially synthesized libraries and can specifically bind to the target molecules. Aptamers can bind and regulate the activities of its target molecules based on their own structure and sequence, and are applied to in vivo molecular function researches and new drug preparation explorations. In recent years, peptide aptamers have been widely used in various fields, such as medicine, genetics and molecular biology, which is becoming a highly efficient, specific and powerful new tool. In plants, with the establishment, application and promotion of the corresponding system, aptamers have gradually been become an effective tool for studying plant molecular functions. In this review, we summarized the classification, screening principles and basic applications of aptamers, with special emphasis on their applications in plant breeding. It can be expected that with the development of molecular design bio-breeding technology, aptamers can be cooperated with transgenic techniques and become a valuable application tool in the plant science fields.

Key words: aptamer, nucleic acid, peptide, plants, screening