SUMO化修饰在植物与病原互作中的功能研究进展

doi:10.11983/CBB25106

摘要/Abstract

摘要： SUMO化修饰是植物中重要的翻译后修饰, 通过介导底物蛋白的功能、免疫信号的激活与转导以及激素信号网络, 在植物免疫调控中发挥关键作用。该文从SUMO化修饰系统的酶联反应机制、SUMO化修饰参与植物免疫调控以及病原体效应蛋白对SUMO化系统的干扰等方面, 系统综述了SUMO化修饰在植物与病原互作中的功能最新研究进展, 旨在解析SUMO化介导的植物免疫调控网络, 为开发基于SUMO化修饰的作物抗病新策略提供参考。

关键词: SUMO化修饰, 病原体, 免疫信号, 激素信号, 效应蛋白

Abstract: SUMOylation is a crucial post-translational modification in plants, playing a pivotal role in plant immune regulation by mediating substrate protein functions, the activation and transduction of immune signals, and hormonal signaling networks. This review systematically summarizes recent research advances in SUMOylation during plant-pathogen interactions, focusing on the enzymatic cascade mechanisms of the SUMOylation system, the involvement of SUMOylation in plant immune regulation, and the interference/activation of the SUMOylation system by pathogen effector proteins. We highlight the SUMOylation-mediated regulatory networks of plant immunity and provide a reference for developing novel disease resistance strategies in crops based on SUMO modification.

Key words: SUMOylation, pathogen, immune signaling, hormonal signaling, effector protein

李文亮, 冯汉青, 赖建彬. SUMO化修饰在植物与病原互作中的功能研究进展. 植物学报, 2025, 60(5): 749-758.

Li Wenliang, Feng Hanqing, Lai Jianbin. Research Progress on SUMOylation in Plant-Pathogen Interactions. Chinese Bulletin of Botany, 2025, 60(5): 749-758.

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链接本文: https://www.chinbullbotany.com/CN/10.11983/CBB25106

https://www.chinbullbotany.com/CN/Y2025/V60/I5/749

图/表 1

图1 SUMO化修饰在植物与病原互作中的免疫调控网络在植物与病原互作中, SUMO化修饰调控真菌细胞致病蛋白、植物细胞中效应蛋白和免疫相关蛋白以及关键转录因子的免疫功能。S: SUMO化修饰; P: 磷酸化; Mo: 水稻稻瘟病菌; Bc: 灰霉菌; Vd: 大丽轮枝菌; SA: 水杨酸; JA: 茉莉酸; HR: 超敏反应; ROS: 活性氧; BR: 油菜素甾醇; ETI: 效应子触发免疫; X: 抑制作用。实线表示直接靶向调控作用; 虚线表示分子调控的双向性。

Figure 1 The immuneity regulatory networks of SUMOylation in plant-pathogen interactions During plant-pathogen interactions, SUMOylation regulates the immune functions of fungal pathogenicity proteins, effector proteins and immunity-associated proteins in plant cells, as well as key transcription factors. S: SUMOylation; P: Phosphorylation; Mo: Magnaporthe oryzae (rice blast fungus); Bc: Botrytis cinerea (gray mold fungus); Vd: Verticillium dahliae (verticillium wilt fungus); SA: Salicylic acid; JA: Jasmonic acid; HR: Hypersensitive response; ROS: Reactive oxygen species; BR: Brassinosteroids; ETI: Effector-triggered immunity; X: Inhibition. Solid lines indicate direct targeting regulatory effects; Dash lines indicate the bidirec tional nature of molecular regulation.

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