Chinese Bulletin of Botany ›› 2008, Vol. 25 ›› Issue (05): 608-615.

• 专题介绍 • Previous Articles     Next Articles

SUMOylation and Its Biological Function in Plants

Panglian Xu, Mianwei Zeng, Lixia Huang, Chengwei Yang*   

  1. Guangdong Provincial Key Laboratory of Biotechnology for Plant Development, College of Life Sciences, South China Normal University, Guangzhou 510631, China
  • Received:2008-03-17 Revised:2008-07-06 Online:2008-09-01 Published:2008-09-01
  • Contact: Chengwei Yang

Abstract: Post-translational modification by small ubiquitin-related modifiers (SUMOs) is an important regulatory process to modulate protein function. This paper summarizes the SUMOylation pathway in plants; the pathway consists of SUMO molecules, a SUMO conjugation enzyme cascade and de-conjugation enzymes. Nascent SUMOs are processed by SUMO-specific proteases, then mature SUMOs are conjugated to substrate proteins by sequential action of three groups of enzymes: SUMO-activating enzymes (E1), SUMO-conjugating enzymes (E2) and SUMO-ligating enzymes (E3). SUMOylation can be reversed by SUMO-specific proteases. SUMO modification in plants is involved in flowering induction, hormone signaling, pathogen defense and stress response.