轮藻门植物与陆生植物组成单系的链形植物门, 化石证据和分子证据认为陆生植物起源于轮藻门植物。该文总结了已完成全基因组测序的10种轮藻门植物的14个全基因组信息, 综述了植物陆地化的分子机制, 表明调控植物激素信号转导和编码关键转录因子的基因家族扩张和水平基因转移是轮藻产生预适应的潜在原因。文中阐述了轮藻门植物全基因组数据在转录组学和基因功能研究中的作用, 提出端粒到端粒的基因组和泛基因组对深入理解植物陆地化的重要性, 以及整合基因组信息和生物学实验在解析轮藻门植物基因功能和起源方面的必要性 。

Charophytes and land plants form a monophyletic group known as Streptophyta. Fossil and molecular evidences suggest that land plants originated from Charophytes. This article summarizes the 14 whole genomes information of 10 Charophytes and reviews the molecular mechanisms involved in the terrestrialization of plants, revealing that the expansion of gene families regulating plant hormone signal transduction and encoding key transcription factors, as well as horizontal gene transfer, are potential reasons for the pre-adaptation of Charophytes. We elucidate the role of whole-genome data of Charophytes in transcriptomics and gene function research. Moreover, we propose the importance of telomere-to-telomere genomes and pan-genome for a deeper understanding of plant terrestrialization and the necessity of integration of genomic data with biological experiments in deciphering the function and origin of Charophytes genes.