植物学报

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植物网格蛋白介导的胞吞作用研究进展

王玉同1,  2†, 杨润林1†,  田丹3†  徐梅4,  廉玉科1,  2,  费琼晖1,  2*,  严旭4*   

  1. 1天水师范大学生物工程与技术学院, 硫生物技术研究所, 天水 741001; 2甘肃省农业固体废弃物资源化利用重点实验室, 天水 741001;  3华南农业大学生命科学学院, 广州 5106423; 4绍兴文理学院生命与环境科学学院, 绍兴 312000


  • 收稿日期:2025-05-27 修回日期:2025-08-18 出版日期:2025-09-05 发布日期:2025-09-05
  • 通讯作者: 费琼晖, 严旭
  • 基金资助:
    国家自然科学基金(No.32200607)、甘肃省科技计划(No.24JRRE005, No.24JRRE007, No.24JRRE008)、浙江省自然科学基金(No.LQ23C160005)和天水师范学院高层次人才科研项目(No.KYQ2023-16)

Research Advances of Clathrin-Mediated Endocytosis in Plants

Yutong Wang1, 2,  Ruilin Yang1,  Dan Tian3,  Mei Xu4, Yuke Lian1, 2,  Qionghui Fei1, 2*,  Xu Yan4*   

  1. 1Institute of Sulfur Biotechnology, School of Bioengineering and Biotechnology, Tianshui Normal University, Tianshui 741001; 2Gansu Key Laboratory of Utilization of Agricultural Solid Waste Resources, Tianshui 741001; 3College of Life Sciences, South China Agricultural University, Guangzhou 510642; 4School of Life and Environmental Sciences, Shaoxing University, Shaoxing 312000

  • Received:2025-05-27 Revised:2025-08-18 Online:2025-09-05 Published:2025-09-05
  • Contact: Qionghui Fei, Xu Yan
  • Supported by:
    Mechanism underlying regulation of autophagy by clathrin and adaptor protein complex AP-4 in plants;Ethylene Signaling Regulates Clathrin-Mediated Membrane Recruitment in Plants;Molecular Mechanism of Adaptor Protein AP-MUTANT in Regulating Plant Fertility

摘要: 网格蛋白介导的胞吞作用(clathrin-mediated endocytosis, CME)是动植物细胞中质膜蛋白进行胞吞的主要途径之一, 网格蛋白及其接头蛋白复合体介导的胞吞作用在植物形态建成、根尖向地性生长、避盐反应、免疫响应、营养元素运输等过程中发挥重要作用。本文以动物细胞网格蛋白及其介导的胞吞作用为基础, 阐述植物网格蛋白及其接头蛋白复合体的组成、定位和生物学功能, 并系统总结了植物CME途径在调控植物生长发育和应对生物与非生物胁迫等生物学过程中的重要作用, 同时对其未来研究方向进行展望, 旨在为深入研究植物CME途径的分子机理提供参考。

关键词: 网格蛋白, 接头蛋白复合体, 网格蛋白介导的胞吞作用, 植物

Abstract: Clathrin-mediated endocytosis (CME) is one of the primary pathways for the internalization of plasma membrane proteins in animal and plant cells. Clathrin and its adaptor protein complexes play crucial roles in plant morphogenesis, root gravitropic growth, halotropism response, immune signaling and nutrient elements. This review begins with an overview of clathrin and its mediated endocytosis in animal cells, briefly summarizing the composition, localization, and biological functions of plant clathrin and its adaptor protein complexes. It focuses on the regulatory mechanisms and biological roles of the CME pathway in plants, while also summarizing and prospecting the critical contributions of CME to plant growth, development, and responses to biotic and abiotic stresses. Furthermore, future research directions are discussed, providing valuable references for ‌in-depth exploration‌ of the ‌molecular mechanisms‌ underlying the plant CME pathway.

Key words: clathrin, adaptor protein complexes, clathrin-mediated endocytosis, plant

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