Recent Advances in Metabolic Products of Flavonoids in Punica granatum
Ancheng Liu, Hui Li, Liangsheng Wang, Changmin Pang, Weiguang Wei
Chinese Bulletin of Botany. 2011, 46(2):
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Pomegranate (Punica granatum) is a cultivated fruit with a long history and great nutritional value. China has 8 major pomegranate-producing areas, including Xingyang and Kaifeng cities, Henan province; Lintong county, Shaanxi province; Zaozhuang county, Shandong province; Huaiyuan county, Anhui province; Huili county, Sichuan province; Mengzi county, Yunnan province; and Kargilik county, Xinjiang Uyghur autonomous region. In total, 33 flavonoids have been detected from pomegranate fruit juice, pericarp and foliage; these include 6 flavanols, 1 flavanone glycoside, 2 flavonols, 3 flavonol glycosides, 3 flavones, 5 flavone glycosides, 1 flavanonol glycoside, 3 anthocyanidins and 9 anthocyanins. These flavonoid compounds are widely used in the health food and medicinal industries. This paper summarizes the recent progress in the constitution, content, detection methods and pharmacological studies of flavonoids in the fruit, leaf and petal of P. granatum. To promote deeper research and use of the active components and for functional characterization for cancer prevention, future study should focus on the rapid analysis, semi-preparation and/or preparation separation, and quantitative analysis of flavonoids in fruits; germplasm resource evaluation; and identification of active components in leaves and flowers of pomegranate.