Received date: 2022-03-04
Accepted date: 2022-05-12
Online published: 2022-05-12
In eucaryotic cells, the endosomal sorting complex required for transport (ESCRT) machinery, consisting of the conserved multiple sub-complexes, plays important roles in both endocytic and secretory pathways. In plant cells, the ESCRT machinery consists of four ESCRT complexes (ESCRT-I, -II, -III, and the VPS4/SKD1 complex) and several ESCRT accessory proteins, but lacks of the ESCRT-0. Every ESCRT complex contains several subunit proteins. Recent researches have demonstrated that the ESCRT machinery plays an essential role in the vacuolar sorting of ubiquitinated membrane proteins via regulation the biogenesis of multivesicular body (MVB)/PVC (prevacuolar compartment) and autophagic pathway. Recent researches have demonstrated that the ESCRT machinery plays an essential role in the vacuolar sorting of ubiquitinated membrane proteins via regulation the biogenesis of multivesicular body (MVB)/PVC (prevacuolar compartment) and autophagosome as well as response to environmental stresses. In this review, we firstly introduce the subunits and biological functions of the ESCRT machinery in plants, and then summarize the latest research advances on the plant-specific ESCRT complex components. Finally, we discuss future study on the unsolved scientific problems of the ESCRT complex in plants.
Key words： ESCRT complex; MVB/PVC; endocytosis
Wu Fan, Shen Jinbo, Hu Shuai . Research Advances of the Plant ESCRT Machinery[J]. Chinese Bulletin of Botany, 2022 , 57(5) : 697 -712 . DOI: 10.11983/CBB22038
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