Studies of Innate Immunity Mediated by Lysin Motif Protein and Its Signaling Priming

doi:10.11983/CBB14119

Abstract

Abstract: Lysin motif (LysM) is a ubiquitous protein domain found in most living organisms. LysM-containing proteins in plant cells can recognize different GlcNAc-containing ligands, thereby triggering specific defense responses to pathogens. As a group of important pattern recognition receptors, LysM-containing proteins trigger downstream signaling by oligomerization, thus interacting with the Botrytis-induced kinase 1 (BIK1) and mitogen-activated protein kinase (MAPK) cascade. Pathogenic microorganisms also use certain mechanisms to escape from pathogen-associated molecular pattern-triggered immunity by utilizing specific recognition or modification of pattern recognition receptors by the secreted effector proteins. This review focuses on the functions of these receptor kinases/proteins in response to elicitor stimuli and priming of defense responses.

Dongchao Ji, Kai Song, Jingjing Xing, Tong Chen, Shiping Tian. Studies of Innate Immunity Mediated by Lysin Motif Protein and Its Signaling Priming[J]. Chinese Bulletin of Botany, 2015, 50(5): 628-636.

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https://www.chinbullbotany.com/EN/Y2015/V50/I5/628

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References 68

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基因名称 (别称)	基因号	LysM结构域布局	配体	受体类型	是否为功能性激酶(激酶类型)	突变体对几丁质处理后的响应	备注
AtCERK1 (AtLYK1, LysM RLK1)	At3g21630	I + II + IV	几丁质	LysM-RLK-I LYK	是 (RD kinase)	不敏感	参与肽聚糖感知; LjNFR1横向同源
AtLYK2	At3g01840	* + * + V	未知	LysM-RLK-II LYR	否 (Pseudo kinase)	正常	LjNFR5横向同源II
AtLYK3	At1g51940	* + VII + *	未知	LysM-RLK-I LYK	是 (RD kinase)	正常
AtLYK4	At2g23770	I + II + III	几丁质	LysM-RLK-II LYR	否 (Pseudo kinase)	中等敏感	LjNFR5横向同源I
AtLYK5	At2g33580	I + II + III	几丁质	LysM-RLK-II LYR	否 (Pseudo kinase)	正常
AtLYP1 (CEBiP-like1, LYM2)	At2g17120	* + VI + VII	几丁质	LYP	-	正常	C末端包含GPI锚定信号; OsCEBiP直系同源
AtLYP2 (CEBiP-like2, LYM1)	At1g21880	* + VI + VIII	肽聚糖	LYP	-	正常	C末端包含GPI锚定信号; 与OsLYP4和OsLYP6直系同源
AtLYP3 (CEBiP-like3, LYM3)	At1g77630	* + VI + VIII	肽聚糖	LYP	-	正常	C末端包含GPI锚定信号; 与OsLYP4和OsLYP6直系同源

基因名称 (别称)	基因号	LysM结构域布局	配体	受体类型	是否为功能性激酶(激酶类型)	突变体对几丁质处理后的响应	备注
AtCERK1 (AtLYK1, LysM RLK1)	At3g21630	I + II + IV	几丁质	LysM-RLK-I LYK	是 (RD kinase)	不敏感	参与肽聚糖感知; LjNFR1横向同源
AtLYK2	At3g01840	* + * + V	未知	LysM-RLK-II LYR	否 (Pseudo kinase)	正常	LjNFR5横向同源II
AtLYK3	At1g51940	* + VII + *	未知	LysM-RLK-I LYK	是 (RD kinase)	正常
AtLYK4	At2g23770	I + II + III	几丁质	LysM-RLK-II LYR	否 (Pseudo kinase)	中等敏感	LjNFR5横向同源I
AtLYK5	At2g33580	I + II + III	几丁质	LysM-RLK-II LYR	否 (Pseudo kinase)	正常
AtLYP1 (CEBiP-like1, LYM2)	At2g17120	* + VI + VII	几丁质	LYP	-	正常	C末端包含GPI锚定信号; OsCEBiP直系同源
AtLYP2 (CEBiP-like2, LYM1)	At1g21880	* + VI + VIII	肽聚糖	LYP	-	正常	C末端包含GPI锚定信号; 与OsLYP4和OsLYP6直系同源
AtLYP3 (CEBiP-like3, LYM3)	At1g77630	* + VI + VIII	肽聚糖	LYP	-	正常	C末端包含GPI锚定信号; 与OsLYP4和OsLYP6直系同源