Abstract: In this paper, the contents of syringin and total flavonoid in different parts of Acanthopanax senticosus according to seasonal dynamics were determined. Syringin mainly exists in branches, stems, rhizomes and roots, but in branches, the average content is 2.94%, which is the highest in all parts of A. secticosus. The syringin content of the aboveground parts shows a distinct seasonal dynamics. It is higher in the spring and autumn but lower in the growth season (summer). However, the syringin content of underground parts does not show a distinct seasonal dynamics. All parts of A. senticosus contain flavonoid. The content of total flavonoid in the leaves shows a distinct dynamics. The highest content, about 3.8%, occurs in the middle of May before the forest canopy closure. The content of total flavonoid in branches and stems also shows a distinct seasonal dynamics: higher in the spring and autumn, but lower in summer. In the branches, the average content of total flavonoid reaches 3.75% in autumn. But the total flavonoid content of the underground parts does not show a distinct seasonal dynamic. The reasons for the seasonal dynamics of the syringin and total flavonoid of A. senticosus are discussed.