植物细胞质外体pH感受机制的解析
收稿日期: 2022-08-19
修回日期: 2022-08-22
网络出版日期: 2022-08-23
基金资助
国家自然科学基金(N0.61521006)
Analysis of the pH Sensing Mechanism of Plant Apoplasts
Received date: 2022-08-19
Revised date: 2022-08-22
Online published: 2022-08-23
质外体是植物感受和应答环境胁迫(包括生物和非生物胁迫)的前沿区域。质外体的pH值是被严格调控的重要生理参数。环境胁迫(如细菌病害)等会引起植物细胞质外体碱化现象。然而, 质外体pH如何协调根生长与免疫响应? 其分子调控机制尚不清楚。最近, 南方科技大学生命科学学院郭红卫团队与清华大学-德国马克斯普朗克研究所-科隆大学柴继杰团队以模式植物拟南芥(Arabidopsis thaliana)为研究材料, 通过遗传学、细胞生物学、生物化学和结构生物学等综合手段, 发现细胞表面小肽-受体复合物可作为质外体pH感受器, 感受和应答分子模式触发的免疫(PTI)引发的拟南芥根尖分生组织细胞质外体碱化。该研究揭示了植物根尖分生组织细胞质外体pH感受的蛋白质复合物及响应机制, 以及免疫与生长之间的协调机制, 加深了人们对植物如何平衡生长与免疫应答生物学反应过程的理解。
杨永青, 郭岩 . 植物细胞质外体pH感受机制的解析[J]. 植物学报, 2022 , 57(4) : 409 -411 . DOI: 10.11983/CBB22198
The apoplast is the frontier area for plants to sense and respond to environmental stresses (including biotic and abiotic stresses). The pH of the apoplast is an important physiological parameter that is tightly regulated. Environmental stress (such as bacterial disease) can cause alkalinization of plant apoplast, but how does apoplast pH coordinate root growth and immune response? Its molecular regulation mechanism is still unclear. Recently, the team of Professor Hongwei Guo from the School of Life Sciences, Southern University of Science and Technology, and the team of Professor Jijie Chai from Tsinghua University-Max Planck Institute of Germany-University of Cologne used the model plant Arabidopsis as research materials, through genetic, cellular, biochemical and structural biology. By means of comprehensive methods, it was found that the small peptide-receptor complex on the cell surface can act as an apoplast pH sensor to sense and respond to the apoplast alkalinization of Arabidopsis root apex meristem cells induced by pattern triggered immunity (PTI). The results of this research have discovered the protein complex and response mechanism of plant root apex meristem apoplast pH sensing, as well as the coordination mechanism between immunity and growth, further understanding the biology reaction process of how plants balance growth and immune response.
Key words： Arabidopsis thaliana; apoplast pH; receptor
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