植物驱动蛋白: 从微管阵列到生理活动调控
收稿日期: 2022-01-12
录用日期: 2022-02-25
网络出版日期: 2022-02-25
基金资助
国家自然科学基金(32072084)
Plant Kinesin: from Microtubule Arrays to Physiological Regulation
Received date: 2022-01-12
Accepted date: 2022-02-25
Online published: 2022-02-25
驱动蛋白(kinesin)是以微管为轨道的分子马达, 其催化ATP水解为ADP, 将贮藏在ATP分子中的化学能高效地转化为机械能, 在细胞形态建成、细胞分裂、细胞运动、胞内物质运输和信号转导等多种生命活动中发挥重要作用。对植物驱动蛋白的研究落后于动物和真菌, 其原因不仅由于植物进化出独有的驱动蛋白家族, 而且其家族成员数量远多于动物驱动蛋白。该文主要总结了驱动蛋白在微管阵列动态组织, 包括周质微管和有丝分裂早前期微管带、纺锤体及成膜体中的角色和功能, 以及其对植物生理活动的调控作用。同时对重要经济作物大豆(Glycine max)中的驱动蛋白进行了系统分析、分类及功能预测, 发现大豆驱动蛋白数量庞大。结合公共数据库中大豆转录组数据, 对部分大豆驱动蛋白进行功能预测, 以期对大豆及其它作物驱动蛋白功能研究提供线索和启示。
王韫慧, 王一帆, 蔺佳雨, 李金红, 姚士恩, 冯湘池, 曹振林, 王俊, 李美娜 . 植物驱动蛋白: 从微管阵列到生理活动调控[J]. 植物学报, 2022 , 57(3) : 358 -374 . DOI: 10.11983/CBB22007
Kinesins are molecular motors that move along microtubules tracks, catalyze the hydrolysis of ATP to ADP, convert the chemical energy stored in ATP molecules into a mechanical force efficiently, and play important roles in various life activities such as cell morphogenesis, cell division, cell movement, intracellular transport, and signal transduction. Plant kinesin research lag behind that of animals and fungi, not only because plants have evolved a unique kinesin family, but also have more members than that of animals. Here we summarize the most recent advancements made towards understanding kinesin functions in the dynamic organization of microtubule arrays, including cortical microtubules and mitotic pre-prophase band, spindle apparatus and phragmoplast, and the regulation of plant physiological activities. We also performed a systematic analysis, classification and functional prediction of kinesins in soybean, the important cash crop, and found that the numbers of soybean kinesins are largely expanded. Taking advantage of the soybean transcriptome data in the public database, the functions of some soybean kinesins were predicted, to provide some clues for the study of kinesin functions in soybean and other crops.
Key words： kinesin; microtubule arrays; physiological regulation; soybean
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