水稻糯性相关基因的全基因组关联分析
# 共同第一作者
收稿日期: 2015-11-11
录用日期: 2016-03-25
网络出版日期: 2016-12-02
基金资助
广西自然科学基金(No.2015GXNSFBA139054, No.2015GXNSFBA139080)、广西科学研究与技术开发计划(No;桂科重14121001-1-6)、广西八桂学者专项经费(No;桂人才通字[2011]4号)和广西农业科学院优势团队(No.2015YT15)
Genome-wide Association Study of Genes Related to Waxiness in Oryza sativa
# Co-first authors
Received date: 2015-11-11
Accepted date: 2016-03-25
Online published: 2016-12-02
利用1 090 071个SNP标记, 对419份广西地方稻种资源核心种质的糯性进行全基因组关联分析。结果表明, 运用混合线性模型, 在P<4.72×10-8 (4.72E-8)水平下, 检测到45个与糯性显著关联的SNP位点, 均位于第6号染色体上。通过筛选显著关联位点上、下游各150 kb区域内的基因, 共找到305个候选基因, 其中包含2个与淀粉合成酶相关的Wx和SSIIa基因; 同时在第6号染色体5.69-5.89 Mb区域发现4个与糯性显著关联的SNP位点, 该区域可能是影响水稻(Oryza sativa)糯性的重要候选区域。
杨行海, 农保选, 夏秀忠, 张宗琼, 曾宇, 刘开强, 邓国富, 李丹婷 . 水稻糯性相关基因的全基因组关联分析[J]. 植物学报, 2016 , 51(6) : 737 -742 . DOI: 10.11983/CBB15204
We examined rice waxiness by genome-wide association study based on genotyping 1 090 071 single nucleotide polymorphism (SNP) variants across landraces in the core collection of 419 rice germplasm derived from Guangxi. We identified 45 significant associated loci located on chromosome 6 at P<4.72×10-8 (4.72E-8) in the compressed mixed linear model. Screening the genes in the candidate regions about 150 kb upstream and downstream of each significant loci revealed 305 candidate genes, including Wx and SSIIa related to starch synthase. Furthermore, 4 significant SNPs associated with waxiness were intensively located in the region of 5.69-5.89 Mb on chromosome 6. This region may be an important candidate region related to waxiness in rice.
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