Precision Engineering of Strigolactone Receptor Aids Rice in Antiviral Defense
Received date: 2026-03-01
Accepted date: 2026-04-10
Online published: 2026-05-20
The RNA interference (RNAi) pathway acts as a conserved and broad-spectrum antiviral defense mechanism in plants, whereas viruses deploy effector proteins to counter host defense. Strigolactones (SLs) are a new class of phytohormones that regulate plant architecture, stress resilience, arbuscular mycorrhizal symbiosis, and parasitic diseases, but their antiviral mechanisms remain unclear. Recent research reveals that SL signaling is a pivotal regulatory node in the arms race between viruses and plants. SLs induce the expression of the transcription factor ONAC131, which acts synergistically with the virus-responsive protein MID1 to enhance antiviral RNAi. However, the rice grassy stunt virus (RGSV) deploys the P3 effector to dampen SL perception by disrupting the interaction between the SL receptor D14 and D3, thereby weakening the antiviral defense of rice. Precise editing of D14 remarkably enhances resistance to RGSV without yield penalty. This work reveals a novel mechanism whereby the SL signaling pathway and the RNAi pathway cooperate to counter viral invasion. It also provides a precise target for antiviral breeding in crops and represents a major breakthrough in the field of plant virology. In light of this, this paper summarizes the research progress on the antiviral RNAi pathway and SL signaling pathway, highlighting the regulatory functions of SL and other phytohormone signaling pathways in the offensive and defensive interactions between plants and viruses. Looking ahead, it offers new insights for the targeted breeding of antiviral crops by identifying key genes in hormone signaling hubs.
Key words: RNAi; strigolactone; rice; receptor D14; antiviral breeding
Jinhua Yang , Bing Wang . Precision Engineering of Strigolactone Receptor Aids Rice in Antiviral Defense[J]. Chinese Bulletin of Botany, 2026 , 61(3) : 357 -368 . DOI: 10.3724/CBB-2026-0044
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|
|
|
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|
|
|
|
|
|
|
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|
|
|
|
|
|
顾红雅, 陈凡, 林荣呈, 漆小泉, 杨淑华, 陈之端, 陈学伟, 丁兆军, 萧浪涛, 左建儒, 姜里文, 白永飞, 种康, 王雷 (2025). 2024年中国植物科学重要研究进展. 植物学报 60, 151-171.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
黎舒佳, 高谨, 李家洋, 王永红 (2015). 独脚金内酯调控水稻分蘖的研究进展. 植物学报 50, 539-548.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Waters MT,
|
|
|
|
|
|
|
|
|
|
|
|
|
|
姚瑞枫, 谢道昕 (2024). 水稻独脚金内酯信号感知的激活和终止. 植物学报 59, 873-877.
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
/
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