Advances
in the
Regulation of Alternative Splicing of Genes in Plants in Response to Abiotic
Stress

XIONG Liang-Lin; LIANG Guo-Lu; GUO Qi-Gao; YING Dan-Long

doi:10.11983/CBB24189

Chinese Bulletin of Botany >

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DOI: https://doi.org/10.11983/CBB24189

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Advances in the Regulation of Alternative Splicing of Genes in Plants in Response to Abiotic Stress

XIONG Liang-Lin ,
LIANG Guo-Lu ,
GUO Qi-Gao ,
YING Dan-Long

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¹Key Laboratory of Agricultural Biosafety and Green Production in the Upper Reaches of the Yangtze River, Ministry of Education, College of Horticulture and Landscape Architecture of Southwest University, Chongqing 400715, China; ²Hanhong College of Southwest University, Chongqing 400715, China

Received date: 2024-12-05

Revised date: 2025-01-20

Online published: 2025-02-26

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Abstract

The external environment plays a crucial role in the growth and development of plants. However, the extreme climates that have occurred frequently in recent years have posed a serious threat to the growth and development of plants. Understanding the regulatory mechanisms of plant stress resistance is of great significance for ensuring the survival and development of plants (especially economic crops) and their yields. Alternative splicing is an important post-transcriptional regulatory mechanism and plays an important role in the diversity of plant gene functions and stress resistance. At present, a variety of alternative splicing variants of stress-resistant related genes have been identified in different plants, and some plant stress-resistant regulatory mechanisms mediated by alternative splicing of genes have been elucidated, effectively promoting the relevant theoretical basis for plant stress resistance research. Therefore, mining and identifying the alternative splicing regulatory mechanisms of more stress-resistant genes under abiotic stress play an important role in plant stress resistance research. This paper reviews the types and splicing mechanisms of alternative splicing of plant genes, focuses on expounding the research progress of plant stress resistance mediated by alternative splicing of related genes under abiotic stress and provides a prospect for the future direction of research on alternative splicing of plant genes.

Key words： plants; gene alternative splicing; regulatory mechanisms; abiotic stress; stress tolerance

Cite this article

XIONG Liang-Lin , LIANG Guo-Lu , GUO Qi-Gao , YING Dan-Long .

Advances in the Regulation of Alternative Splicing of Genes in Plants in Response to Abiotic Stress[J]. Chinese Bulletin of Botany, 0 : 1 -0 . DOI: 10.11983/CBB24189

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References

[1]Albaqami M, Laluk K, Reddy ASN(2019).The Arabidopsis splicing regulator SR45 confers salt tolerance in a splice isoform dependent manner.Plant Mol Biol, 100:379-390. [2]Alhabsi A, Butt H, Kirschner GK, Blilou I, Mahfouz MM(2023).SCR106 splicing factor modulates abiotic stress responses by maintaining RNA splicing in rice.J Exp Bot, 75:802-818. [3]BARNABáS B, J?GER K, FEHéR A(2008).The effect of drought and heat stress on reproductive processes in cereals.Plant Cell, Environ31:11-38. [4]Blencowe BJ(2006).Alternative Splicing: New Insights from Global Analyses.Cell, 126:37-47. [5]Butt H, Bazin J, Prasad KVSK, Awad N, Crespi M, Reddy ASN, Mahfouz MM (2022).The Rice Serine/Arginine Splicing Factor RS33 Regulates Pre-mRNA Splicing during Abiotic Stress Responses. cells 11, 1796..cells, :-. [6]Calixto CPG, Guo WB, James AB, Tzioutziou NA, Entizne JC, Panter PE, Knight H, Nimmo HG, Zhang RX, and Brown JWS(2018).Rapid and Dynamic Alternative Splicing Impacts the Arabidopsis Cold Response Transcriptome.Plant Cell, 30:1424-1444. [7]Calixto CPG, Tzioutziou NA, James AB, Hornyik C, Guo WB, Zhang RX, Nimmo HG, Brown JWS (2019).Cold-Dependent Expression and Alternative Splicing of Arabidopsis Long Non-coding RNAs. Front Plant Sci 10, 235.., :-. [8]Charng YY, Liu HC, Liu NY, Chi WT, Wang CN, Chang SH, Wang TT(2007).A Heat-Inducible Transcription Factor,HsfA2,Is Required for Extension of Acquired Thermotolerance in Arabidopsis.Plant Physiol, 143:251-262. [9]Chen YH, Weng X, Zhou XX, Gu JB, Hu Q, Luo QW, Wen MF, Li C, Wang ZY (2022).Overexpression of cassava RSZ21b enhances drought tolerance in Arabidopsis. J Plant Physiol 268, 153574.., :-. [10]Cho S, Hoang A, Sinha R, Zhong XY, Fu XD, Krainer AR, Ghosh G(2011).Interaction between the RNA binding domains of Ser-Arg splicing factor 1 and U1-70K snRNP protein determines early spliceosome assembly.PNAS, 108:8233-8238. [11]Cui P, Zhang SD, Ding F, Ali S, Xiong LM (2014).Dynamic regulation of genome-wide pre-mRNA splicing and stress tolerance by the Sm-like protein LSm5 in Arabidopsis. Genome Biol 15, R1.., :-. [12]de Francisco Amorim M, Willing E-M, Szabo EX, Francisco-Mangilet AG, Droste-Borel I, Ma?ek B, Schneeberger K, Laubinger S(2018).The U1 snRNP Subunit LUC7 Modulates Plant Development and Stress Responses via Regulation of Alternative Splicing.Plant Cell, 30:2838-2854. [13]Ding F, Cui P, Wang ZY, Zhang SD, Ali S, Xiong LM (2014).Genome-wide analysis of alternative splicing of pre-mRNA under salt stress in Arabidopsis. BMC Genomics 15, 431.., :-. [14]Egawa C, Kobayashi F, Ishibashi M, Nakamura T, Nakamura C, Takumi S(2006).Differential regulation of transcript accumulation and alternative splicing of a DREB2 homolog under abiotic stress conditions in common wheat.Genes Genet Syst, 81:77-91. [15]ERKELENZ S, MUELLER WF, EVANS MS, BUSCH A, SC?NEWEIS K, HERTEL KJ, SCHAAL H(2013).Position-dependent splicing activation and repression by SR and hnRNP proteins rely on common mechanisms.RNA, 19:96-102. [16]Fedoroff NV, Battisti DS, Beachy RN, Cooper PJM, Fischhoff DA, Hodges CN, Knauf VC, Lobell D, Mazur BJ, Molden D, Reynolds MP, Ronald PC, Rosegrant MW, Sanchez PA, Vonshak A, Zhu JK(2010).Radically Rethinking Agriculture for the 21st Century.Science, 327:833-8343. [17]Feng JL, Li JJ, Gao ZX, Lu YR, Yu JY, Zheng Q, Yan SN, Zhang WJ, He H, Ma LG, Zhu ZG(2015).SKIP Confers Osmotic Tolerance during Salt Stress by Controlling Alternative Gene Splicing in Arabidopsis.Mol Plant, 8:1038-1052. [18]Feng JL, Li JJ, Gao ZX, Lu YR, Yu JY, Zheng Q, Yan SN, Zhang WJ, He H, Ma LG, Zhu ZG(2015).SKIP Confers Osmotic Tolerance during Salt Stress by Controlling Alternative Gene Splicing in Arabidopsis.Mol Plant, 8:1038-1052. [19]Gallegos J(2018).Alternative Splicing Plays a Major Role in Plant Response to Cold Temperatures.Plant Cell, 30:1378-1379. [20]Gan JH, Qiu YQ, Tao YL, Zhang LN, Okita TW, Yan YY, Tian L (2024).RNA-seq analysis reveals transcriptome reprogramming and alternative splicing during early response to salt stress in tomato root. Front Plant Sci 15, 1394223.., :-. [21]Graveley BR(2001).Alternative splicing: Increasing diversity in the proteomic world.Trends Genet, 17:100-107. [22]Gu JB, Ma SY, Zhang YN, Wang D, Cao SQ, Wang ZY(2020).Genome-Wide Identification of Cassava SerineArginine-Rich Proteins: Insights into Alternative Splicing of Pre-mRNAs and Response to Abiotic Stress.Plant Cell Physiol, 61:178-191. [23]Gu JB, Xia ZQ, Luo YH, Jiang XY, Qian BL, Xie H, Zhu JK, Xiong LM, Zhu JH, Wang ZY(2018).Spliceosomal protein U1A is involved in alternative splicing and salt stress tolerance in Arabidopsis thaliana.Nucleic Acids Res, 46:1777-1792. [24]Guan QM, Wu JM, Zhang YY, Jiang CH, Liu RY, Chai CL, Zhu JH(2013).A DEAD Box RNA Helicase Is Critical for Pre-mRNA Splicing,Cold-Responsive Gene Regulation,and Cold Tolerance in Arabidopsis.Plant Cell, 25:342-356. [25]Guo XK, Wang TP, Jiang LY, Qi H, Zhang ZD (2023).PlaASDB: a comprehensive database of plant alternative splicing events in response to stress. BMC Plant Biol 23, 225., :-. [26]Haung R, Jin ZY, Zhang DH, Li LZ, Zhou JX, Xiao L, Li P, Zhang MJ, Tian CD, Zhang WK, Zhong LS, Quan MY, Zhao R, Du L, Liu LJ, Li ZH, Zhang DQ, Du QZ(2024).Rare variations within the serinearginine-rich splicing factor PtoRSZ21 modulate stomatal size to determine drought tolerance in Populus.New phytol, 243:1776-1794. [27]Hong YC, Gao Y, Pang J, Shi HZ, Li TT, Meng HY, Kong DL, Chen YJ, Zhu JK, Wang Z(2023).The Sm core protein SmEb regulates salt stress responses through maintaining proper splicing of RCD1 pre‐mRNA in Arabidopsis.J Integr Plant Biol, 65:1383-1393. [28]Huertas R, Catalá R, Jiménez-Gómez JM, Castellano MM, Crevillén P, Pi?eiro M, Jarillo JA, Salinas J(2019).Arabidopsis SME1 Regulates Plant Development and Response to Abiotic Stress by Determining Spliceosome Activity Specificity.Plant Cell, 31:537-554. [29]Ikeda M, Mitsuda N, Ohme-Takagi M(2011).Arabidopsis HsfB1 and HsfB2b Act as Repressors of the Expression of Heat-Inducible Hsfs But Positively Regulate the Acquired Thermotolerance.Plant Physiol, 157:1243-1254. [30]Ings J, Mur LAJ, Robson PRH, Bosch M (2013).Physiological and growth responses to water deficit in the bioenergy crop Miscanthus x giganteus. Front Plant Sci 4, 468., :-. [31]Ishida T, Yoshimura M, Miura K, Sugimoto K (2012).MMS21/HPY2andSIZ1, TwoArabidopsisSUMOE3 Ligases, Have Distinct Functions in Development. PLOS ONE 7, e46897.., :-. [32]Jian YQ, Chen X, Sun KW, Lu ZY, Cheng DN, Cao J, Liu JZ, Cheng XF, Wu L, Zhang F, Luo YM, Hahn M, Ma ZH, Yin YY(2023).SUMOylation regulates pre-mRNA splicing to overcome DNA damage in fungi.New Phytol, 237:2298-2315. [33]Jiang JF, Liu XN, Liu CH, Liu GT, Li SH, Wang LJ(2017).Integrating Omics and Alternative Splicing Reveals Insights into Grape Response to High Temperature.Plant Physiol, 173:1502-1518. [34]Kerbler SM, Wigge PA(2023).Temperature Sensing in Plants.Annu Rev Plant Biol, 74:341-366. [35]Kim T, Hwang H, Bang G, Ha JM, Park YJ, Kim JY (2024).Understanding the molecular mechanisms of drought tolerance in wild soybean (Glycine soja) through multi-omics-based alternative splicing predictions. Environ Exp Bot 225, 105872.., :-. [36]Kwak JS, Song JT, Seo HS(2024).E3 SUMO ligase SIZ1 splicing variants localize and function according to external conditions.Plant Physiol, 195:1601-1623. [37]Laloum T, Martín G, Duque P(2018).Alternative Splicing Control of Abiotic Stress Responses.Trend Plant Sci, 23:140-150. [38]Lee BH, Kapoor A, Zhu JH, Zhu JK(2006).STABILIZED1,a Stress-Upregulated Nuclear Protein,Is Required for Pre-mRNA Splicing,mRNA Turnover,and Stress Tolerance in Arabidopsis.Plant Cell, 18:1736-1749. [39]Li SX, Yu X, Cheng ZH, Zeng CY, Li WB, Zhang LS, Peng M(2020).Large-scale analysis of the cassava transcriptome reveals the impact of cold stress on alternative splicing.J Exp Bot, 71:422-434. [40]Ling Y, Alshareef S, Butt H, Lozano-Juste J, Li LX, Galal AA, Moustafa A, Momin AA, Tashkandi M, Richardson DN, Fujii H, Arold S, Rodriguez PL, Duque P, Mahfouz MM(2017).Pre-mRNA splicing repression triggers abiotic stress signaling in plants.Plant J, 89:291-309. [41]Ling Y, Mahfouz MM, Zhou SX(2021).Pre-mRNA alternative splicing as a modulator for heat stress response in plants.Trends Plant Sci, 26:1153-1170. [42]Liu JJ, Sun N, Liu M, Liu JC, Du BJ, Wang XJ, Qi XT(2013).An Autoregulatory Loop Controlling Arabidopsis HsfA2 Expression: Role of Heat Shock-Induced Alternative Splicing.Plant Physiol, 162:512-521. [43]Liu SR, Li B, Liang QX, Liu AR, Qu LH, Yang JH (2020).Classification and function of RNA-protein interactions. Wiley Interdiscip Rev RNA 11, e1601.., :-. [44]Liu X, Long ML, Chen JC, Zhang R, Wang YY, Xiao JL, Ding XD, Zhang SZ, Li Q (2024).A global survey of bicarbonate stress-induced pre-mRNA alternative splicing in soybean via integrative analysis of Iso-seq and RNA-seq. Int J Biol Macromol 278, 135067.., :-. [45]Liu YM, Cao L, Wu X, Wang S, Zhang PM, Li ML, Jiang JH, Ding XD, Cao XY (2023).Functional characterization of wild soybean (Glycine soja) GsSnRK1.1 protein kinase in plant resistance to abiotic stresses. J Plant Physiol 280, 153881.., :-. [46]Liu ZS, Qin JX, Tian XJ, Xu SB, Wang Y, Li HX, Wang XM, Peng HR, Yao YY, Hu ZR, Ni ZR, Xin MM, Sun QX(2018).Global profiling of alternative splicing landscape responsive to drought,heat and their combination in wheat (Triticum aestivum L.Plant Biotechnol J, 16:714-726. [47]LOPATO S, MAYEDA A, KRAINER AR, BARTA A(1996).Pre-mRNA splicing in plants: Characterization of SerArg splicing factors.PNAS, 93:3074-3079. [48]Lorkovi? ZJ, Kirk DAW, Lambermon MHL, Filipowicz W(2000).Pre-mRNA splicing in higher plants.Trends Plant Sci, 5:160-167. [49]Lu CA, Huang CK, Huang WS, Huang TS, Liu HY, Chen YF(2020).DEAD-BoxRNAHelicase42PlaysaCriticalRolein Pre-mRNA Splicing under Cold Stress.Plant Physiol, 182:255-271. [50]Lu CA, Huang CK, Huang WS, Huang TS, Liu HY, Chen YF(2020).DEAD-Box RNA Helicase 42 Plays a Critical Role in Pre-mRNA Splicing under Cold Stress.Plant Physiol, 182:255-271. [51]Lu FZ, Li WC, Peng YL, Cao Y, Qu JT, Sun FA, Yang QQ, Lu YL, Zhang XH, Zhang XH, Zheng LJ, Fu FL, Yu HQ (2022).ZmPP2C26 Alternative Splicing Variants Negatively Regulate Drought Tolerance in Maize. Front Plant Sci 13, 851531.., :-. [52]Lv JJ, Zhou FF, Wei QQ, Long XQ, Tian WJ, Zhai JJ, Wang JJ, Zhang Q, Wan DS (2024).An alternative 3′ splice site of PeuHKT1; 3 improves the response to salt stress through enhancing affinity to K+ in Populus. Plant Physiol Biochem 212, 108776.., :-. [53]Manley JL, Tacke R(1996).SR proteins and splicing control.Genes Dev, 10:1569-1579. [54]Matera AG, Wang ZF(2014).A day in the life of the spliceosome.Nat Rev Mol Cell Biol, 15:108-121. [55]Matsukura S, Mizoi J, Yoshida T, Todaka D, Ito Y, Maruyama K, Shinozaki K, Yamaguchi-Shinozaki K(2010).Comprehensive analysis of rice DREB2-type genes that encode transcription factors involved in the expression of abiotic stress-responsive genes.Mol Genet Genomics, 283:185-196. [56]Mi XZ, Tang MS, Zhu JX, Shu MT, Wen HL, Zhu JY, Wei CL (2024).Alternative splicing of CsWRKY21 positively regulates cold response in tea plant. Plant Physiol Biochem 208, 108473.., :-. [57]Miura K, Furumoto T(2013).Cold Signaling and Cold Response in Plants.Int J Mol Sci, 4:5312-5337. [58]Miura K, Rus A, Sharkhuu A, Yokoi S, Karthikeyan AS, Raghothama KG, Baek D, Koo YD, Jin JB, Bressan RA, Yun DJ, Hasegawa PM(2005).The Arabidopsis SUMO E3 ligase SIZ1 controls phosphate deficiency responses.PNAS, 102:7760-7765. [59]Muthusamy M, Yoon EK, Kim JA, Jeong MJ, Lee SI (2020).Brassica Rapa SR45a Regulates Drought Tolerance via the Alternative Splicing of Target Genes. genes 11, 182.., :-. [60]Ner-Gaon H, Halachmi R, Savaldi-Goldstein S, Rubin E, Ophir R, Fluhr R(2004).Intron retention is a major phenomenon in alternative splicing in Arabidopsis.Plant J, 39:877-885. [61]Ner-Gaon H, Halachmi R, Savaldi-Goldstein S, Rubin E, Ophir R, Fluhr R(2004).Intron retention is a major phenomenon in alternative splicing in Arabidopsis.Plant J, 39:877-885. [62]Nishizawa A, Yabuta Y, Yoshida E, Maruta T, Yoshimura K, Shigeoka S(2006).Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.Plant J, 48:535-547. [63]Palusa SG, Reddy ASN(2015).Differential Recruitment of Splice Variants from SR Pre-mRNAs to Polysomes During Development and in Response to Stresses.Plant Cell Physiol, 56:421-427. [64]Paul T, Zhang PC, Zhang ZH, Fargason T, De Silva NIU, Powell E, Ekpenyong E, Jamal S, Yu YB, Prevelige P, Lu R, Zhang J (2024).TheU1-70K and SRSF1 interaction is modulated by phosphorylation during the early stages of spliceosome assembly. Protein Sci 33, e5117.., :-. [65]Punzo P, Grillo S, Batelli G(2020).Alternative splicing in plant abiotic stress responses.Biochem Soc Trans, 48:2117-2126. [66]Remy E, Cabrito TR, Baster P, Batista RA, Teixeira MC, Friml J, Sá-Correia I, Duque P(2013).A Major Facilitator Superfamily Transporter Plays a Dual Role in Polar Auxin Transport and Drought Stress Tolerance in Arabidopsis.Plant Cell, 25:901-926. [67]Rosenkranz RRE, Vraggalas S, Keller M, Sankaranarayanan S, McNicoll F, L?chli K, Bublak D, Benhamed M, Crespi M, Berberich T, Bazakos C, Feldbrügge M, Schleiff E, Müller-McNicoll M, Zarnack K, Fragkostefanakis S(2024).A plant-specific clade of serine arginine-rich proteins regulates RNA splicing homeostasis and thermotolerance in tomato.Nucleic Acids Res, 52:11466-11480. [68]Seo PJ, Park MJ, Park CM(2013).Alternative splicing of transcription factors in plant responses to low temperature stress: mechanisms and functions.Planta, 237:1415-1424. [69]Song L, Pan ZZ, Chen L, Dai Y, Wan JR, Ye H, Nguyen HT, Zhang GZ, Chen HT (2020).Analysis of Whole Transcriptome RNA-seq Data Reveals Many Alternative Splicing Events in Soybean Roots under Drought Stress Conditions. Genes 11, 1520.., :-. [70]Staiger D, Brown JWS(2013).Alternative Splicing at the Intersection of Biological Timing,Development,and Stress Responses.Plant Cell, 25:3640-3656. [71]Sun Q, Sun YX, Li X, Li ML, Li Q, Xiao JL, Xu PF, Zhang SZ, Ding XD(2024).Regulation of plant resistance to salt stress by the SnRK1-dependent splicing factor SRRM1L.New Phytol, 242:2093-2114. [72]Syed NH, Kalyna M, Marquez Y, Barta A, Brown JWS(2012).Alternative splicing in plants-coming of age.Trends Plant Sci, 17:1360-1385. [73]Tanabe N, Yoshimura K, Kimura A, Yabuta Y, Shigeoka S(2006).Differential Expression of Alternatively Spliced mRNAs of Arabidopsis SR Protein Homologs,atSR30 and atSR45a,in Response to Environmental Stress.Plant Cell Physiol, 48:1036-1049. [74]Tian L, Zhao XY, Liu HH, Ku LX, Wang SX, Han ZP, Wu LC, Shi Y, Song XH, Chen YH (2019).Alternative splicing of ZmCCA1 mediates drought response in tropical maize. PLOS ONE 14, e0211623.., :-. [75]Wang F, Li Y, Yuan JB, Li Y, Gu JB, Wang ZY(2024).The U1 small nuclear RNA enhances drought tolerance in Arabidopsis.Plant Physiol, 196:1126-1146. [76]Wang X, Liu Y, Ouyang L, Yao RN, Yu TT, Yan LY, Chen YN, Huai DX, Zhou XJ, Wang ZH, Kang YP, Wang QQ, Jiang HF, Lei Y, Liao BS (2024).Full-length transcriptome sequencing provides insights into alternative splicing under cold stress in peanut. Front Plant Sci 15, 1362277.., :-. [77]Wang XX, Wu FM, Xie QG, Wang HM, Wang Y, Yue YL, Gahura O, Ma SS, Liu L, Cao Y, Jiao YL, Puta F, McClung CR, Xu XD, Ma LG(2012).SKIP Is a Component of the Spliceosome Linking Alternative Splicing and the Circadian Clock in Arabidopsis.Plant Cell, 24:3278-3295. [78]Wang Z, Hong YC, Yao JJ, Huang H, Qian BL, Liu X, Chen YJ, Pang J, Zhan XQ, Zhu JK, Zhu JH(2022).Modulation of plant development and chilling stress responses by alternative splicing events under control of the spliceosome protein SmEb in Arabidopsis.Plant Cell Environ, 45:2762-2779. [79]Wen JJ, Qin Z, Sun L, Zhang YM, Wang DL, Peng HR, Yao YY, Hu ZR, Ni ZF, Sun QX, Xin MM(2023).Alternative splicing of TaHSFA6e modulates heat shock protein–mediated translational regulation in response to heat stress in wheat.New phytol, 239:2235-2247. [80]Will CL, Lührmann R (2011).Spliceosome Structure and Function. Cold Spring Harb Perspect Biol 3, a003707.., :-. [81]Yamaguchi-Shinozak K, Shinozaki K(2006).Transcriptional Regulatory Networks in Cellular Responses and Tolerance to Dehydration and Cold Stresses.Annu Rev Plant Biol, 57:781-803. [82]Yao H, Li GZ, Gao ZZ, Guo F, Feng JH, Xiao GH, Shen HT, Li HB (2024).Alternative splicing responses to salt stress in Glycyrrhiza uralensis revealed by global profiling of transcriptome RNA-seq datasets. Front Genet 15, 1397502.., :-. [83]Yu ZP, Huang X, Wen SH, Cao HJ, Wang N, Shen SH, Ding MQ (2023).Alternative Splicing under Cold Stress in Paper Mulberry. Plants 12, 3950.., :-. [84]ZAHLER AM, ROTH MB(1995).Distinct functions of SR proteins in recruitment of U1 small nuclear ribonucleoprotein to alternative 5' splice sites.PNAS, 92:2642-2646. [85]Zhang WT, Du BJ, Liu D, Qi XT(2014).Splicing factor SR34b mutation reduces cadmium tolerance in Arabidopsis by regulating iron-regulated transporter 1 gene.Biochem Biophys Re Commun, 455:312-317. [86]Zhang WX, Wang H, Guo YN, Hao XY, Li YX, He WT, Zhao X, Cai SY, Song XB(2024).Functional Validation of Different Alternative Splicing Variants of the Chrysanthemum lavandulifolium ClNUM1 Gene in Tobacco.Curr Issues Mol Biol, 46:5242-5256. [87]Zhang YL, Chen ZT, Tian HW, Wu YM, Kong Y, Wang XM, Sui N(2024).Alternative Splicing Plays a Crucial Role in the Salt Tolerance of Foxtail Millet.J Agric Food Chem, 72:10814-10827. [88]Zhong YY, Luo YH, Sun JL, Qin XM, Gan P, Zhou ZW, Qian YQ, Zhao RP, Zhao ZY, Cai WG, Luo JJ, Chen LL, Song JM(2024).Pan-transcriptomic analysis reveals alternative splicing control of cold tolerance in rice.Plant Cell, 36:2117-2139. [89]Zhou H, Shi H, Yang YQ, Feng XX, Chen X, Xiao F, Lin HH, Guo Y(2023).Insights into plant salt stress signaling and tolerance.J Genet Genomics, 51:16-34.

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