Research Advances in Cyclic Nucleotide-gated Ion Channels in Plants

doi:10.11983/CBB24119

Abstract

Abstract: Cyclic nucleotide-gated channels (CNGCs) are important cation channels that play pivotal roles in the regulation of growth and development, as well as in response to stresses such as cold, heat, salt, and pathogen attacks in plants. In this review, we briefly outline the classification, structure and location of CNGCs in plants, and comprehensively summarize the recent research progress on their ionic selectivity, regulatory mechanisms, and biological functions, in order to enhance our understanding of plant CNGCs and provide a reference for future research.

Key words: stress tolerance, CNGCs, ionic selectivity, response to stress

Yaqi Shi, Haishuang Liu, Jin Ke, Qing Ma, Suomin Wang. Research Advances in Cyclic Nucleotide-gated Ion Channels in Plants[J]. Chinese Bulletin of Botany, 2025, 60(2): 294-306.

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URL: https://www.chinbullbotany.com/EN/10.11983/CBB24119

https://www.chinbullbotany.com/EN/Y2025/V60/I2/294

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References 101

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蛋白	亚细胞定位	组织特异性	可渗透离子	功能	参考文献
AtCNGC1	质膜	根	Ca²⁺、Mg²⁺和Pb²⁺	根的向地性生长; 重金属离子吸收	Sunkar et al., 2000; Ma et al., 2006, 2024; Moon et al., 2019
AtCNGC2	质膜	叶脉末端周围的细胞	Ca²⁺、Mg²⁺、K⁺、Li⁺、Cs⁺、Rb⁺、Sr²⁺和Ba²⁺	植物免疫; 叶片衰老; 耐热、耐寒性; 成花转变; 生长素稳态	Leng et al., 1999, 2002; Ma et al., 2010; Finka et al., 2012; Chin et al., 2013; Tian et al., 2019; Cui et al., 2020; Chakraborty et al., 2021
AtCNGC3	质膜	根表皮及皮层、叶脉	Na⁺和K⁺	离子稳态; 种子萌发; 植物免疫	Gobert et al., 2006
AtCNGC4	质膜	叶表皮、胚轴、根毛区、根的伸长区和分生区	Ca²⁺、Mg²⁺、Ba²⁺、Sr²⁺、K⁺、Na⁺和Cs⁺	植物免疫; 程序性细胞死亡; 耐热、耐寒性; 成花转变	Balagué et al., 2003; Finka et al., 2012; Chin et al., 2013; Tian et al., 2019; Cui et al., 2020
AtCNGC5	质膜	保卫细胞和根毛	Ca²⁺、Mg²⁺和Ba²⁺	耐盐性; 根毛生长; 生长素信号	Wang et al., 2013; Tan et al., 2020, 2023
AtCNGC6	质膜	保卫细胞和根毛	Ca²⁺、Mg²⁺和Ba²⁺	耐盐性; 根毛生长; 生长素信号; 耐热性	Gao et al., 2012; Wang et al., 2013; Brost et al., 2019; Tan et al., 2020, 2023
AtCNGC7 AtCNGC8	质膜	花粉管尖端	Ca²⁺	花粉管生长	Tunc-Ozdemir et al., 2013a; Pan et al., 2019
AtCNGC9	质膜	保卫细胞和根毛	Ca²⁺	根毛生长; 生长素信号	Brost et al., 2019; Tan et al., 2020; 2023
AtCNGC10	质膜、内质网及高尔基体囊泡	叶肉细胞、叶片栅栏薄壁组织、叶表皮、根表皮及内皮层和花	Na⁺、K⁺和Pb²⁺	离子稳态; 耐盐性; 根向地性生长; 花粉发育	Li et al., 2005; Christopher et al., 2007; Guo et al., 2008; Jin et al., 2015; Moon et al., 2019
AtCNGC11	质膜	-	Ca²⁺、Pb²⁺和Cd²⁺	植物免疫; 细胞死亡	Urquhart et al., 2007; Moeder et al., 2011; Moon et al., 2019
AtCNGC12	质膜	保卫细胞	Ca²⁺和Mg²⁺	植物免疫; 细胞死亡; 生长素信号	Urquhart et al., 2007; Moeder et al., 2011; DeFalco et al., 2016; Tan et al., 2023
AtCNGC13	-	-	Pb²⁺和Cd²⁺	重金属离子吸收	Moon et al., 2019
AtCNGC14	质膜	根毛	Ca²⁺	根毛生长; 根的向地性生长	Shih et al., 2015; Zhang et al., 2017; Brost et al., 2019; Serre et al., 2023
AtCNGC15	质膜及核膜	主根和侧根的根尖、侧根原基和保卫细胞	Ca²⁺、Pb²⁺和Cd²⁺	根的发育	Moon et al., 2019; Leitão et al., 2019; Wang et al., 2021b
AtCNGC16	-	花粉管	Ca²⁺和Cd²⁺	逆境胁迫下的花粉育性	Tunc-Ozdemir et al., 2013b; Moon et al., 2019
AtCNGC17	质膜	-	Ca²⁺和K⁺	细胞扩张; 耐盐性	Ladwig et al., 2015
AtCNGC18	质膜	花粉管尖端	Ca²⁺	花粉管的生长和导向	Gao et al., 2016; Pan et al., 2019
AtCNGC19	质膜	叶脉周围的叶肉细胞和根韧皮部	Ca²⁺、Na⁺、Pb²⁺和Cd²⁺	植物免疫; 耐盐性; 植食反应; 细胞死亡	Kugler et al., 2009; Moon et al., 2019; Meena et al., 2019; Yu et al., 2019, 2023; Jogawat et al., 2020
AtCNGC20	质膜	叶脉周围的叶肉细胞	Ca²⁺、Na⁺和Cd²⁺	植物免疫; 耐盐性; 细胞死亡; 耐寒性	Kugler et al., 2009; Yu et al., 2019, 2023; Oranab et al., 2021; Peng et al., 2024

蛋白	亚细胞定位	组织特异性	可渗透离子	功能	参考文献
AtCNGC1	质膜	根	Ca²⁺、Mg²⁺和Pb²⁺	根的向地性生长; 重金属离子吸收	Sunkar et al., 2000; Ma et al., 2006, 2024; Moon et al., 2019
AtCNGC2	质膜	叶脉末端周围的细胞	Ca²⁺、Mg²⁺、K⁺、Li⁺、Cs⁺、Rb⁺、Sr²⁺和Ba²⁺	植物免疫; 叶片衰老; 耐热、耐寒性; 成花转变; 生长素稳态	Leng et al., 1999, 2002; Ma et al., 2010; Finka et al., 2012; Chin et al., 2013; Tian et al., 2019; Cui et al., 2020; Chakraborty et al., 2021
AtCNGC3	质膜	根表皮及皮层、叶脉	Na⁺和K⁺	离子稳态; 种子萌发; 植物免疫	Gobert et al., 2006
AtCNGC4	质膜	叶表皮、胚轴、根毛区、根的伸长区和分生区	Ca²⁺、Mg²⁺、Ba²⁺、Sr²⁺、K⁺、Na⁺和Cs⁺	植物免疫; 程序性细胞死亡; 耐热、耐寒性; 成花转变	Balagué et al., 2003; Finka et al., 2012; Chin et al., 2013; Tian et al., 2019; Cui et al., 2020
AtCNGC5	质膜	保卫细胞和根毛	Ca²⁺、Mg²⁺和Ba²⁺	耐盐性; 根毛生长; 生长素信号	Wang et al., 2013; Tan et al., 2020, 2023
AtCNGC6	质膜	保卫细胞和根毛	Ca²⁺、Mg²⁺和Ba²⁺	耐盐性; 根毛生长; 生长素信号; 耐热性	Gao et al., 2012; Wang et al., 2013; Brost et al., 2019; Tan et al., 2020, 2023
AtCNGC7 AtCNGC8	质膜	花粉管尖端	Ca²⁺	花粉管生长	Tunc-Ozdemir et al., 2013a; Pan et al., 2019
AtCNGC9	质膜	保卫细胞和根毛	Ca²⁺	根毛生长; 生长素信号	Brost et al., 2019; Tan et al., 2020; 2023
AtCNGC10	质膜、内质网及高尔基体囊泡	叶肉细胞、叶片栅栏薄壁组织、叶表皮、根表皮及内皮层和花	Na⁺、K⁺和Pb²⁺	离子稳态; 耐盐性; 根向地性生长; 花粉发育	Li et al., 2005; Christopher et al., 2007; Guo et al., 2008; Jin et al., 2015; Moon et al., 2019
AtCNGC11	质膜	-	Ca²⁺、Pb²⁺和Cd²⁺	植物免疫; 细胞死亡	Urquhart et al., 2007; Moeder et al., 2011; Moon et al., 2019
AtCNGC12	质膜	保卫细胞	Ca²⁺和Mg²⁺	植物免疫; 细胞死亡; 生长素信号	Urquhart et al., 2007; Moeder et al., 2011; DeFalco et al., 2016; Tan et al., 2023
AtCNGC13	-	-	Pb²⁺和Cd²⁺	重金属离子吸收	Moon et al., 2019
AtCNGC14	质膜	根毛	Ca²⁺	根毛生长; 根的向地性生长	Shih et al., 2015; Zhang et al., 2017; Brost et al., 2019; Serre et al., 2023
AtCNGC15	质膜及核膜	主根和侧根的根尖、侧根原基和保卫细胞	Ca²⁺、Pb²⁺和Cd²⁺	根的发育	Moon et al., 2019; Leitão et al., 2019; Wang et al., 2021b
AtCNGC16	-	花粉管	Ca²⁺和Cd²⁺	逆境胁迫下的花粉育性	Tunc-Ozdemir et al., 2013b; Moon et al., 2019
AtCNGC17	质膜	-	Ca²⁺和K⁺	细胞扩张; 耐盐性	Ladwig et al., 2015
AtCNGC18	质膜	花粉管尖端	Ca²⁺	花粉管的生长和导向	Gao et al., 2016; Pan et al., 2019
AtCNGC19	质膜	叶脉周围的叶肉细胞和根韧皮部	Ca²⁺、Na⁺、Pb²⁺和Cd²⁺	植物免疫; 耐盐性; 植食反应; 细胞死亡	Kugler et al., 2009; Moon et al., 2019; Meena et al., 2019; Yu et al., 2019, 2023; Jogawat et al., 2020
AtCNGC20	质膜	叶脉周围的叶肉细胞	Ca²⁺、Na⁺和Cd²⁺	植物免疫; 耐盐性; 细胞死亡; 耐寒性	Kugler et al., 2009; Yu et al., 2019, 2023; Oranab et al., 2021; Peng et al., 2024