U-box E3 Ubiquitin Ligases Regulate Stress Tolerance and Growth of Plants

doi:10.11983/CBB15128

Abstract

Abstract: Ubiquitin-mediated proteolysis is an integral part of diverse cellular functions. As a component of the ubiquitin conjugation system, E3 ubiquitin ligase is the key element determining the substrate specificity of ubiquitination. E3 ligase plays an important role against various environmental stresses such as drought, salinity, chilling, and pathogen attack and has a function in plant growth and development. There are 4 different types of E3 ubiquitin ligases: RING, U-box, HECT, and F-box. We summarize the recent progress in the function of U-box E3 ubiquitin ligases in plant biotic/abiotic stress resistance and development. We also discuss possible directions that might provide valuable information for further research of the regulation of ubiquitin-mediated plant proteolysis.

Li Jiao, Shufang Fu, Yali Zhang, Jiang Lu. U-box E3 Ubiquitin Ligases Regulate Stress Tolerance and Growth of Plants[J]. Chinese Bulletin of Botany, 2016, 51(5): 724-735.

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https://www.chinbullbotany.com/EN/Y2016/V51/I5/724

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References 73

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名称	来源	功能	正调控+/ 负调控-		调控蛋白	参考文献
生物胁迫
AtPUB12, AtPUB13	拟南芥(Arabidopsis thaliana)	参与PTI途径	-		FLS2	Lu et al., 2011
AtPUB17	拟南芥(A. thaliana)	参与ETI途径, HR反应	+		未知	Yang et al., 2006
AtPUB20 (AtCMPG1)	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞核和细胞质	+		AGB1	Heise et al., 2002; Kobayashi et al., 2012
AtPUB21	拟南芥(A. thaliana)	参与PTI途径	-		未知	Gawehns et al., 2013
AtPUB22	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞质	-		Exo70B2	Trujillo et al., 2008; Stegmann et al., 2012
AtPUB23, AtPUB24	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞质	-		未知	Trujillo et al., 2008
MAC3A, MAC3B	拟南芥(A. thaliana)	参与ETI途径, 定位于细胞核	+		AtCDC5	Monaghan et al., 2009
CMPG1-V	簇毛麦(Haynaldia villosa)	与白粉病抗性有关	+		未知	Zhu et al., 2015
CERBERUS	百脉根(Lotus japonicus)	与根瘤形成有关	-		未知	Yano et al., 2009
LIN	百脉根(L. japonicus), 蒺藜苜蓿(Medicago truncatula)	与根瘤形成有关	未知		未知	Kiss et al., 2009
MtPUB1	蒺藜苜蓿(M. truncatula)	与根瘤形成有关, 定位于细胞膜	-		LYK3	Mbengue et al., 2010; Hervé et al., 2011
NtCMPG1, SlCMPG1 (ACRE74)	烟草(Nicotiana tabacum), 番茄(Solanum lycopersicum)	参与ETI途径, HR反应	+		未知	González-Lamothe et al., 2006
NbPUB17, StPUB17 (ACRE276)	本氏烟草(N. benthamiana), 马铃薯(Solanum tuberosum)	参与PTI途径, PCD反应; 定位于细胞核	+		未知	He et al., 2015
OsPUB15	水稻(Oryza sativa)	参与PCD, 固有免疫反应	+		PID2	Wang et al., 2015b
OsSPL11	水稻(O. sativa)	参与PCD, HR反应	-		未知	Bae and Kim, 2013
AvrPtoB	丁香假单胞菌(Pseudomonas syringae) pv. tomato	效应蛋白	未知		未知	Spallek et al., 2009
Avr3a	致病疫霉(Phytophthora infestans)	RxLR类效应蛋白	未知		CMPG1	Bos et al., 2010
非生物胁迫
AtCHIP	拟南芥(A. thaliana)	低温/高温/干旱	未知		PP2A	Yan et al., 2003; Luo et al., 2006
AtPUB18, AtPUB19	拟南芥(A. thaliana)	盐胁迫/干旱	未知		未知	Bergler and Hoth, 2011; Liu et al., 2011; Seo et al., 2012
AtPUB22, AtPUB23	拟南芥(A. thaliana)	干旱	-		RPN6	Cho et al., 2008; Kurepa et al., 2009; Cho et al., 2015
AtPUB30	拟南芥(A. thaliana)	盐胁迫	-		未知	Hwang et al., 2015
BrPUBs	油菜(Brassica rapa)	低温/高温	未知		未知	Wang et al., 2015a
BgBG55	木榄(Bruguiera gymnorrhiza)	盐胁迫	未知		未知	Samuel et al., 2006
CaPUB1	甜椒(Capsicum annuum)	盐胁迫/干旱/损伤	未知		RPN6	Cho et al., 2006
OsPUB15	水稻(O. sativa)	H₂O₂ /盐胁迫/干旱	+		未知	Park et al., 2011
StPUB17	马铃薯(S. tuberosum)	盐胁迫/损伤	+		未知	Ni et al., 2010
名称	来源	功能	正调控+/ 负调控-		调控蛋白	参考文献
VaPUB	山葡萄(Vitis amurensis)	低温/盐胁迫	未知		未知	Jiao et al., 2015
生长发育
AtPUB4	拟南芥(A. thaliana)	雄性不育, 根部细胞增殖和分裂	未知		未知		Wang et al., 2013; Kinoshita et al., 2015
AtPUB8	拟南芥(A. thaliana)	自交不亲和	未知		SRK		Liu et al., 2007
AtPUB9	拟南芥(A. thaliana)	侧根生长发育	未知		ARK1/ ARK2		Deb et al., 2014
AtPUB13	拟南芥(A. thaliana)	影响开花时间	未知		未知		Li et al., 2012
AtPUB20	拟南芥(A. thaliana)	在花粉、花药、未成熟种子和花托中表达	未知		AGB1		Kobayashi et al., 2012
AtPUB21	拟南芥(A. thaliana)	在花药中表达	未知		未知		Kobayashi et al., 2012
AtPUB43	拟南芥(A. thaliana)	种子萌发和早期生长	未知		未知		Salt et al., 2011
AtPUB44 (SAUL1)	拟南芥(A. thaliana)	抑制植株早衰, 与种子萌发和生长发育有关	未知		未知		Drechsel et al., 2011 Salt et al., 2011
BnARC1	油菜(B. napus)	自交不亲和, 花粉管生长, 在柱头表达	+		未知		Newbigin and Vierstra, 2003; Stone et al., 2003; Zhang et al., 2014
CrPUB	衣藻(Chlamydomonas reinhardtii)	脂类代谢	未知		未知		Luo et al., 2015
NtPUB4	烟草(N. tabacum)	调控绒毯层细胞生长和降解	未知		CHRK1		Kim et al., 2003
OsPUB15	水稻(O. sativa)	调节活性氧的产生和细胞死亡, 定位于细胞质	+		未知		Park et al., 2011
OsSPL11	水稻(O. sativa)	调节开花时间, 在细胞核发挥作用	未知		SPIN1		Vega-Sánchez et al., 2008
OsTUD1	水稻(O. sativa)	与细胞增殖有关	未知		G protein α subunit D1/RGA		Hu et al., 2013
植物激素、茉莉酸、水杨酸
AtCHIP	拟南芥(A. thaliana)	脱落酸	未知	未知			Luo et al., 2006
AtPUB9	拟南芥(A. thaliana)	脱落酸	未知	ARK1/ ARK2			Samuel et al., 2008
AtPUB10	拟南芥(A. thaliana)	茉莉酸, 定位于细胞核	未知	MYC2			Jung et al., 2015
AtPUB18, AtPUB19	拟南芥(A. thaliana)	脱落酸	-	未知			Liu et al., 2011; Seo et al., 2012
StPHOR1	马铃薯(S. tuberosum)	赤霉素, 定位于细胞质	+	未知			Amador et al., 2001
StPUB17	马铃薯(S. tuberosum)	茉莉酸、水杨酸、脱落酸、乙烯	未知	未知			Ni et al., 2010

名称	来源	功能	正调控+/ 负调控-		调控蛋白	参考文献
生物胁迫
AtPUB12, AtPUB13	拟南芥(Arabidopsis thaliana)	参与PTI途径	-		FLS2	Lu et al., 2011
AtPUB17	拟南芥(A. thaliana)	参与ETI途径, HR反应	+		未知	Yang et al., 2006
AtPUB20 (AtCMPG1)	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞核和细胞质	+		AGB1	Heise et al., 2002; Kobayashi et al., 2012
AtPUB21	拟南芥(A. thaliana)	参与PTI途径	-		未知	Gawehns et al., 2013
AtPUB22	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞质	-		Exo70B2	Trujillo et al., 2008; Stegmann et al., 2012
AtPUB23, AtPUB24	拟南芥(A. thaliana)	参与PTI途径, 定位于细胞质	-		未知	Trujillo et al., 2008
MAC3A, MAC3B	拟南芥(A. thaliana)	参与ETI途径, 定位于细胞核	+		AtCDC5	Monaghan et al., 2009
CMPG1-V	簇毛麦(Haynaldia villosa)	与白粉病抗性有关	+		未知	Zhu et al., 2015
CERBERUS	百脉根(Lotus japonicus)	与根瘤形成有关	-		未知	Yano et al., 2009
LIN	百脉根(L. japonicus), 蒺藜苜蓿(Medicago truncatula)	与根瘤形成有关	未知		未知	Kiss et al., 2009
MtPUB1	蒺藜苜蓿(M. truncatula)	与根瘤形成有关, 定位于细胞膜	-		LYK3	Mbengue et al., 2010; Hervé et al., 2011
NtCMPG1, SlCMPG1 (ACRE74)	烟草(Nicotiana tabacum), 番茄(Solanum lycopersicum)	参与ETI途径, HR反应	+		未知	González-Lamothe et al., 2006
NbPUB17, StPUB17 (ACRE276)	本氏烟草(N. benthamiana), 马铃薯(Solanum tuberosum)	参与PTI途径, PCD反应; 定位于细胞核	+		未知	He et al., 2015
OsPUB15	水稻(Oryza sativa)	参与PCD, 固有免疫反应	+		PID2	Wang et al., 2015b
OsSPL11	水稻(O. sativa)	参与PCD, HR反应	-		未知	Bae and Kim, 2013
AvrPtoB	丁香假单胞菌(Pseudomonas syringae) pv. tomato	效应蛋白	未知		未知	Spallek et al., 2009
Avr3a	致病疫霉(Phytophthora infestans)	RxLR类效应蛋白	未知		CMPG1	Bos et al., 2010
非生物胁迫
AtCHIP	拟南芥(A. thaliana)	低温/高温/干旱	未知		PP2A	Yan et al., 2003; Luo et al., 2006
AtPUB18, AtPUB19	拟南芥(A. thaliana)	盐胁迫/干旱	未知		未知	Bergler and Hoth, 2011; Liu et al., 2011; Seo et al., 2012
AtPUB22, AtPUB23	拟南芥(A. thaliana)	干旱	-		RPN6	Cho et al., 2008; Kurepa et al., 2009; Cho et al., 2015
AtPUB30	拟南芥(A. thaliana)	盐胁迫	-		未知	Hwang et al., 2015
BrPUBs	油菜(Brassica rapa)	低温/高温	未知		未知	Wang et al., 2015a
BgBG55	木榄(Bruguiera gymnorrhiza)	盐胁迫	未知		未知	Samuel et al., 2006
CaPUB1	甜椒(Capsicum annuum)	盐胁迫/干旱/损伤	未知		RPN6	Cho et al., 2006
OsPUB15	水稻(O. sativa)	H₂O₂ /盐胁迫/干旱	+		未知	Park et al., 2011
StPUB17	马铃薯(S. tuberosum)	盐胁迫/损伤	+		未知	Ni et al., 2010
名称	来源	功能	正调控+/ 负调控-		调控蛋白	参考文献
VaPUB	山葡萄(Vitis amurensis)	低温/盐胁迫	未知		未知	Jiao et al., 2015
生长发育
AtPUB4	拟南芥(A. thaliana)	雄性不育, 根部细胞增殖和分裂	未知		未知		Wang et al., 2013; Kinoshita et al., 2015
AtPUB8	拟南芥(A. thaliana)	自交不亲和	未知		SRK		Liu et al., 2007
AtPUB9	拟南芥(A. thaliana)	侧根生长发育	未知		ARK1/ ARK2		Deb et al., 2014
AtPUB13	拟南芥(A. thaliana)	影响开花时间	未知		未知		Li et al., 2012
AtPUB20	拟南芥(A. thaliana)	在花粉、花药、未成熟种子和花托中表达	未知		AGB1		Kobayashi et al., 2012
AtPUB21	拟南芥(A. thaliana)	在花药中表达	未知		未知		Kobayashi et al., 2012
AtPUB43	拟南芥(A. thaliana)	种子萌发和早期生长	未知		未知		Salt et al., 2011
AtPUB44 (SAUL1)	拟南芥(A. thaliana)	抑制植株早衰, 与种子萌发和生长发育有关	未知		未知		Drechsel et al., 2011 Salt et al., 2011
BnARC1	油菜(B. napus)	自交不亲和, 花粉管生长, 在柱头表达	+		未知		Newbigin and Vierstra, 2003; Stone et al., 2003; Zhang et al., 2014
CrPUB	衣藻(Chlamydomonas reinhardtii)	脂类代谢	未知		未知		Luo et al., 2015
NtPUB4	烟草(N. tabacum)	调控绒毯层细胞生长和降解	未知		CHRK1		Kim et al., 2003
OsPUB15	水稻(O. sativa)	调节活性氧的产生和细胞死亡, 定位于细胞质	+		未知		Park et al., 2011
OsSPL11	水稻(O. sativa)	调节开花时间, 在细胞核发挥作用	未知		SPIN1		Vega-Sánchez et al., 2008
OsTUD1	水稻(O. sativa)	与细胞增殖有关	未知		G protein α subunit D1/RGA		Hu et al., 2013
植物激素、茉莉酸、水杨酸
AtCHIP	拟南芥(A. thaliana)	脱落酸	未知	未知			Luo et al., 2006
AtPUB9	拟南芥(A. thaliana)	脱落酸	未知	ARK1/ ARK2			Samuel et al., 2008
AtPUB10	拟南芥(A. thaliana)	茉莉酸, 定位于细胞核	未知	MYC2			Jung et al., 2015
AtPUB18, AtPUB19	拟南芥(A. thaliana)	脱落酸	-	未知			Liu et al., 2011; Seo et al., 2012
StPHOR1	马铃薯(S. tuberosum)	赤霉素, 定位于细胞质	+	未知			Amador et al., 2001
StPUB17	马铃薯(S. tuberosum)	茉莉酸、水杨酸、脱落酸、乙烯	未知	未知			Ni et al., 2010