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植物学报 >

2023 , Vol. 58 >Issue 6: 946 - 955

DOI: https://doi.org/10.11983/CBB23070

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蛋白液-液相分离调控植物发育及胁迫应答研究进展

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  • 1中国科学院植物研究所, 植物多样性与特色经济作物全国重点实验室, 北京 100093
    2国家植物园, 北京 100093
    3中国科学院大学, 北京 100049

收稿日期: 2023-05-29

  录用日期: 2023-08-09

  网络出版日期: 2023-11-13

基金资助

国家自然科学基金(32072637);国家自然科学基金(31930086);北京市自然科学基金(6212025)

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Advances in the Regulation of Protein Liquid-liquid Phase Separation on Development and Stress Responses in Plants

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  • 1State Key Laboratory of Plant Diversity and Special Crops, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    2China National Botanical Garden, Beijing 100093, China
    3University of Chinese Academy of Sciences, Beijing 100049, China

Received date: 2023-05-29

  Accepted date: 2023-08-09

  Online published: 2023-11-13

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摘要

细胞是生物体结构和功能的基本单位, 有膜或无膜包裹的细胞器在细胞内特定的空间各司其职。然而, 无膜细胞器的形成机制和功能仍有待进一步解析。研究表明, 液-液相分离(LLPS)可以使细胞内的特定分子聚集形成凝聚体, 进而发挥重要作用。随着植物中LLPS研究的不断深入, 相分离形成的凝聚体在植物生长发育和胁迫应答过程中的作用备受关注。该文对蛋白液-液相分离调节植物生长发育以及胁迫应答的研究进展进行综述, 为深入研究LLPS在植物细胞中的工作机制提供参考。

关键词： 液-液相分离; 无膜细胞器; 分子凝聚体

本文引用格式

黄鑫华, 刘伟, 田世平, 陈彤 . 蛋白液-液相分离调控植物发育及胁迫应答研究进展[J]. 植物学报, 2023 , 58(6) : 946 -955 . DOI: 10.11983/CBB23070

Abstract

Cells are basic units of structure and function for organisms, in which membranous and membraneless organelles exert their respective functions in a given space. However, the mechanism underlying the formation and function of membraneless organelles still requires further investigation. It has been shown that liquid-liquid phase separation (LLPS) of proteins may provide a specific way for biomacromolecules within cells to aggregate and form agglomerates, then proceed to play important roles. With increasing reports on LLPS in plants, great interest has been in exploring the roles of phase separation-forming agglutinates in plant growth and development and immune processes. In this review, we mainly focus on the progress of current studies on the role of protein liquid-liquid phase separation in regulating plant growth and development as well as stress responses, which may provide references for further studies on the mechanism of LLPS in plant cells.

Key words： liquid-liquid phase separation; membraneless organelles; biomolecular condensates

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