点击化学反应在植物细胞标记中的应用

张御格, 袁笑妍, 张贵芳, 李雨健, 殷金环, 林金星, 李晓娟

The Application of Click Chemistry Reactions in Plant Cell Labeling

Yuge Zhang, Xiaoyan Yuan, Guifang Zhang, Yujian Li, Jinhuan Yin, Jinxing Lin, Xiaojuan Li

图1 环加成反应的2种反应类型CuAAC (A)和SPAAC (B) CuAAC采用端基炔烃和叠氮化物在铜离子催化下形成1,4-二取代-1,2,3-三唑; SPAAC利用环辛炔和叠氮化物反应形成稳定的三唑。CuAAC: 铜(I)催化的叠氮-炔烃环化加成反应; SPAAC: 张力促进的叠氮-炔烃环化加成反应

Figure 1 Two types of cycloadditions reactions CuAAC (A) and SPAAC (B) CuAAC uses end-group alkynes and azides to form 1,4-disubstituted-1,2,3-triazole catalyzed by copper ions; SPAAC uses cyclooctyne and azide reactions to form stable triazoles. CuAAC: Copper (I) catalysed azide-alkyne cycloaddition; SPAAC: Strain-promoted azide-alkyne cycloaddition