质膜蛋白动力学的调控及其研究方法

罗鹏云, 钱虹萍, 刘艳, 徐昌文, 崔亚宁

Regulation of Plasma Membrane Protein Dynamics and Its Research Methods

Pengyun Luo, Hongping Qian, Yan Liu, Changwen Xu, Yaning Cui

图1 质膜蛋白动力学影响因素 (A) 正常条件下, 质膜蛋白在膜上运动; (B) 纤维素合成抑制剂处理改变质膜蛋白的横向扩散; (C) 微丝/微管抑制剂处理改变质膜蛋白的横向扩散; (D) MβCD处理改变质膜蛋白的横向扩散。

Figure 1 Factors affecting the dynamics of plasma membrane protein (A) Plasma membrane proteins are relatively stationary on the membrane under normal conditions; (B) The lateral diffusion of plasma membrane proteins was changed when the cell wall was damaged by cellulose synthesis inhibitors; (C) Microfilament/microtubule inhibitor treatment disrupts the cytoskeleton and changes the lateral diffusion movement of plasma membrane proteins; (D) MβCD treatment destroys the membrane raft and changes the lateral diffusion of plasma membrane proteins.