活性氧调控植物细胞自噬的研究进展
马丹颖,季东超,徐勇,陈彤(),田世平
Advances in the Regulation on Autophagy by Reactive Oxygen Species in Plant Cells
Danying Ma,Dongchao Ji,Yong Xu,Tong Chen(),Shiping Tian

图1. 植物细胞中不同来源的活性氧调控自噬(改自Pérez-Pérez et al., 2012b)
定位于质膜的NADPH氧化酶, 以及叶绿体、线粒体、过氧化物酶体和内质网等细胞器均能产生活性氧。过量的活性氧会诱导细胞自噬, 以减少活性氧的产生并清除细胞受损组分。NADPH: 烟酰胺腺嘌呤二核苷酸磷酸; O2: 氧分子; O2·-: 超氧阴离子; H2O2: 过氧化氢; 1O2: 单线态氧

Figure 1. Different reactive oxygen species (ROS) sources control autophagy in plant cells (modified from Pérez-Pérez et al., 2012b)
ROS can be generated by plasma membrane-localized NOX and different organelles, including chloroplast, mitochondria, peroxisome, and endoplasmic reticulum. Excess ROS then induce autophagy, which contributes to down-regulate ROS production and remove damaged cellular components. NADPH: Reduced nicotinamide adenine dinucleotide phosphate; O2: Dioxygen; O2·-: Superoxide anion; H2O2: Hydrogen peroxide; 1O2: Singlet oxygen