植物NAD(P)+的生物合成及其生物学功能研究进展

  • 胡海涛 ,
  • 武越 ,
  • 杨玲
展开
  • 浙江师范大学

收稿日期: 2024-09-19

  修回日期: 2024-10-10

  网络出版日期: 2024-10-31

基金资助

浙江省自然科学基金

Research progress on NAD(P)+ biosynthesis and function in plants

  • HU Hai-Shou ,
  • WU Huo ,
  • YANG Ling
Expand

Received date: 2024-09-19

  Revised date: 2024-10-10

  Online published: 2024-10-31

摘要

烟酰胺腺嘌呤二核甘酸(nicotinamide adenine dinucleotide, NAD+)和烟酰胺腺嘌呤二核苷酸磷酸(nicotinamide adenine dinucleotide phosphate, NADP+)是植物核心能量代谢、生长发育进程调节以及胁迫应答的整合者,可直接或间接影响许多关键的细胞功能。作为细胞代谢的基石,维持胞内NAD(P)+的稳态对协调植物细胞正常能量代谢、生长发育和胁迫应答平衡至关重要。NAD(P)+的合成受损或缺乏会引发植物细胞代谢紊乱和一系列缺陷表型,严重时会导致植物体的死亡。目前,植物中NAD(P)+合成途径及其关键酶已研究得比较清晰,而其在植物体内生物合成、转运、消耗以及回收的调控机制尚不清楚。因此,挖掘NAD(P)+缺乏相关突变体对解析植物细胞内NAD(P)+稳态的调节机制以及其对植物生长发育和胁迫应答的调控机理具有重要意义。本文综述了植物NAD(P)+的生物合成代谢途径以及关键酶,重点阐述了NAD(P)+参与调节植物生长发育和胁迫应答过程,并展望了植物NAD(P)+的研究前景。

本文引用格式

胡海涛 , 武越 , 杨玲 . 植物NAD(P)+的生物合成及其生物学功能研究进展[J]. 植物学报, 0 : 1 -0 . DOI: 10.11983/CBB24144

Abstract

Nicotinamide adenine dinucleotide (NAD+) and nicotinamide adenine dinucleotide phosphate (NADP+) acts as an integral regulator of core energy metabolism, regulation of growth and development process and stress response in plants, which can directly and indirectly influence many key cellular functions. As the cornerstone of cell metabolism, the maintenance of intracellular NAD(P)+ homeostasis is crucial for normal plant growth and development, and stress response. Impaired or deficient synthesis of NAD(P)+ in plant cell can trigger metabolic disorders and a series of defective phenotypes, and may even lead to plant death in severe cases. Currently, NAD(P)+ biosynthesis pathway and its key enzymes have been well studied in plants. However, the regulatory mechanisms of its synthesis, translocation, consumption, and recycling transformations in plants are still unclear. Isolating NAD(P)+ deficient mutants is crucial for analyzing the regulatory mechanisms of NAD(P)+ homeostasis in plants and and its regulation of plant development and stress responses. This paper reviews the biosynthetic metabolic pathways of plant NAD(P)+, focuses on the participation of NAD(P)+ in plant growth and development, and stress response processes, and looks forward to the research prospects of plant NAD(P)+.
文章导航

/