Calcium/calmodulin-mediated Signal Transduction System in Plants

doi:10.11983/CBB15201

Abstract

Abstract: Calcium (Ca²⁺) is an important second messenger in plant responses to diverse cellular and environmental stimuli. Calmodulin (CaM) and calmodulin-like proteins (CMLs) are major Ca²⁺ sensors to decode Ca²⁺ signals. Although CaM and CMLs have no enzymatic activity or biochemical functions, they are considered multifunctional regulatory proteins by regulating the activity of various classes of downstream CaM/CML-binding proteins (CBPs) and therefore are involved in multiple cellular processes during plant growth and development and environmental adaptation. In this review, we summarize studies of plant CBPs and their physiological functions, methods for identifying CBPs, mechanisms of CBP regulation by Ca²⁺/CaMs, and CaM-mediated signal transduction pathways related to protein phosphorylation and dephosphorylation, transcriptional regulation of gene expression, ion transportation, reactive oxygen species metabolism, hormone and phospholipid signals, the possible future directions are also discussed.

Houqing Zeng, Yaxian Zhang, Shang Wang, Xiajun Zhang, Huizhong Wang, Liqun Du. Calcium/calmodulin-mediated Signal Transduction System in Plants[J]. Chinese Bulletin of Botany, 2016, 51(5): 705-723.

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https://www.chinbullbotany.com/EN/Y2016/V51/I5/705

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蛋白种类		蛋白名称	物种	生理功能	参考文献
激酶和磷酸酶		CBK3	拟南芥	抗热击	Liu et al., 2008
		NtCBK1	烟草	开花调控	Hua et al., 2004
		NtCaMK1	烟草	未知	Ma et al., 2004
		CRLK1	拟南芥	抗冷冻	Yang et al., 2010
		CCaMK	苜蓿、水稻和玉米	共生, 抗氧化防御	Gleason et al., 2006; Ma et al., 2012; Shi et al., 2012; Routray et al., 2013
		MPK8	拟南芥	损伤反应, ROS平衡	Takahashi et al., 2011
		PP7	拟南芥	抗热击	Kutuzov et al., 2001; Liu et al., 2007
		MKP1	拟南芥	抗病、抗紫外、抗盐和抗基因毒性	Ulm et al., 2002; Lee et al., 2008; Bartels et al., 2009; Gonzalez Besteiro et al., 2011
		OsMKP1	水稻	损伤反应	Katou et al., 2007
		NtMKP1	烟草	抗病虫害和机械损伤	Yamakawa et al., 2004; Oka et al., 2013
		PCaMPP	苔藓	未知	Takezawa, 2003
转录因子和辅助因子		CAMTA3	拟南芥	通用胁迫反应, 抗冷冻和抗病虫害	Doherty et al., 2009; Du et al., 2009; Bjornson et al., 2014
		CBP60g	拟南芥	抗病	Wang et al., 2009; Zhang et al., 2010
		WRKY7	拟南芥	抗病	Park et al., 2005; Kim et al., 2006
		MYB2	拟南芥	ABA信号, 盐胁迫, 叶片衰老, 缺磷反应	Abe et al., 2003; Yoo et al., 2005; Guo and Gan, 2011; Baek et al., 2013
		MYB91	拟南芥	叶片发育	Han et al., 2012
		CBNAC	拟南芥	未知	Kim et al., 2007
		TGA3	拟南芥	抗病和抗重金属胁迫	Szymanski et al., 1996; Choi et al., 2010; Farinati et al., 2010
		IQD1	拟南芥	抗虫	Levy et al., 2005
		GT2L	拟南芥	抗冷, 抗盐	Xi et al., 2012
		BT2	拟南芥	端粒酶活性, 糖和ABA信号, 配子体发育	Du and Poovaiah, 2004; Ren et al., 2007; Mandadi et al., 2009; Robert et al., 2009
		PCBP	马铃薯	未知	Reddy et al., 2002
离子通道和膜蛋白		ACA2	拟南芥	抗盐	Anil et al., 2008
		ACA4	拟南芥	抗盐和抗病	Geisler et al., 2000; Boursiac et al., 2010
		ACA8	拟南芥	抗病	dit Frey et al., 2012
		ACA11	拟南芥	抗病	Boursiac et al., 2010
		CNGC1	拟南芥	抗重金属胁迫	Sunkar et al., 2000
		CNGC2	拟南芥	抗病	Clough et al., 2000; Ali et al., 2007
		CNGC3	拟南芥	Na⁺/K⁺吸收, 抗盐	Gobert et al., 2006
		CNGC4	拟南芥	抗病	Balague et al., 2003
		CNGC10	拟南芥	K⁺吸收, 抗盐	Li et al., 2005; Guo et al., 2008
		CNGC11	拟南芥	抗病	Yoshioka et al., 2006
		CNGC12	拟南芥	抗病	Yoshioka et al., 2006
		NHX1	拟南芥	抗盐	Yamaguchi et al., 2005
		PEN3	拟南芥	抗病	Campe et al., 2015
		Apyrase1	拟南芥	花粉萌发, 细胞生长	Steinebrunner et al., 2000; Wu et al., 2007
		MLO	水稻和大麦	抗病	Kim et al., 2002a, 2002b
		CIP111	拟南芥	未知	Buaboocha et al., 2001
		AFG1L1	拟南芥	未知	Bussemer et al., 2009
代谢酶		CAT3	拟南芥	ROS清除	Yang and Poovaiah, 2002b
		ELP	常绿大戟	ROS平衡	Medda et al., 2003; Mura et al., 2005
		NtGAD	烟草	氨基丁酸合成	Baum et al., 1996
蛋白种类	蛋白名称		物种	生理功能	参考文献
	NADK		烟草和拟南芥	NADP(H)合成, ROS产生	Harding et al., 1997; Turner et al., 2004
	DWF1		拟南芥	油菜素内酯合成	Du and Poovaiah, 2005
	LeCBDGK		番茄	磷脂酸合成	Snedden and Blumwald, 2000
	PsTic32		豌豆	叶绿体蛋白移动	Chigri et al., 2006
其它CBPs	MPCBP		玉米	花粉萌发	Safadi et al., 2000
	ZmSAUR1		玉米	生长素信号	Yang and Poovaiah, 2000a; Knauss et al., 2003
	Ch-CPN10		拟南芥	未知	Yang and Poovaiah, 2000b
	NPG1		拟南芥	花粉萌发	Golovkin and Reddy, 2003
	KCBP		拟南芥	细胞分裂, 表皮毛形成	Reddy et al., 1996; Reddy et al., 2004
	DRL1		拟南芥	分裂组织活性, 器官生长	Nelissen et al., 2003
	UBP6		拟南芥	未知	Moon et al., 2005
	IQM1		拟南芥	气孔运动	Zhou et al., 2012

蛋白种类		蛋白名称	物种	生理功能	参考文献
激酶和磷酸酶		CBK3	拟南芥	抗热击	Liu et al., 2008
		NtCBK1	烟草	开花调控	Hua et al., 2004
		NtCaMK1	烟草	未知	Ma et al., 2004
		CRLK1	拟南芥	抗冷冻	Yang et al., 2010
		CCaMK	苜蓿、水稻和玉米	共生, 抗氧化防御	Gleason et al., 2006; Ma et al., 2012; Shi et al., 2012; Routray et al., 2013
		MPK8	拟南芥	损伤反应, ROS平衡	Takahashi et al., 2011
		PP7	拟南芥	抗热击	Kutuzov et al., 2001; Liu et al., 2007
		MKP1	拟南芥	抗病、抗紫外、抗盐和抗基因毒性	Ulm et al., 2002; Lee et al., 2008; Bartels et al., 2009; Gonzalez Besteiro et al., 2011
		OsMKP1	水稻	损伤反应	Katou et al., 2007
		NtMKP1	烟草	抗病虫害和机械损伤	Yamakawa et al., 2004; Oka et al., 2013
		PCaMPP	苔藓	未知	Takezawa, 2003
转录因子和辅助因子		CAMTA3	拟南芥	通用胁迫反应, 抗冷冻和抗病虫害	Doherty et al., 2009; Du et al., 2009; Bjornson et al., 2014
		CBP60g	拟南芥	抗病	Wang et al., 2009; Zhang et al., 2010
		WRKY7	拟南芥	抗病	Park et al., 2005; Kim et al., 2006
		MYB2	拟南芥	ABA信号, 盐胁迫, 叶片衰老, 缺磷反应	Abe et al., 2003; Yoo et al., 2005; Guo and Gan, 2011; Baek et al., 2013
		MYB91	拟南芥	叶片发育	Han et al., 2012
		CBNAC	拟南芥	未知	Kim et al., 2007
		TGA3	拟南芥	抗病和抗重金属胁迫	Szymanski et al., 1996; Choi et al., 2010; Farinati et al., 2010
		IQD1	拟南芥	抗虫	Levy et al., 2005
		GT2L	拟南芥	抗冷, 抗盐	Xi et al., 2012
		BT2	拟南芥	端粒酶活性, 糖和ABA信号, 配子体发育	Du and Poovaiah, 2004; Ren et al., 2007; Mandadi et al., 2009; Robert et al., 2009
		PCBP	马铃薯	未知	Reddy et al., 2002
离子通道和膜蛋白		ACA2	拟南芥	抗盐	Anil et al., 2008
		ACA4	拟南芥	抗盐和抗病	Geisler et al., 2000; Boursiac et al., 2010
		ACA8	拟南芥	抗病	dit Frey et al., 2012
		ACA11	拟南芥	抗病	Boursiac et al., 2010
		CNGC1	拟南芥	抗重金属胁迫	Sunkar et al., 2000
		CNGC2	拟南芥	抗病	Clough et al., 2000; Ali et al., 2007
		CNGC3	拟南芥	Na⁺/K⁺吸收, 抗盐	Gobert et al., 2006
		CNGC4	拟南芥	抗病	Balague et al., 2003
		CNGC10	拟南芥	K⁺吸收, 抗盐	Li et al., 2005; Guo et al., 2008
		CNGC11	拟南芥	抗病	Yoshioka et al., 2006
		CNGC12	拟南芥	抗病	Yoshioka et al., 2006
		NHX1	拟南芥	抗盐	Yamaguchi et al., 2005
		PEN3	拟南芥	抗病	Campe et al., 2015
		Apyrase1	拟南芥	花粉萌发, 细胞生长	Steinebrunner et al., 2000; Wu et al., 2007
		MLO	水稻和大麦	抗病	Kim et al., 2002a, 2002b
		CIP111	拟南芥	未知	Buaboocha et al., 2001
		AFG1L1	拟南芥	未知	Bussemer et al., 2009
代谢酶		CAT3	拟南芥	ROS清除	Yang and Poovaiah, 2002b
		ELP	常绿大戟	ROS平衡	Medda et al., 2003; Mura et al., 2005
		NtGAD	烟草	氨基丁酸合成	Baum et al., 1996
蛋白种类	蛋白名称		物种	生理功能	参考文献
	NADK		烟草和拟南芥	NADP(H)合成, ROS产生	Harding et al., 1997; Turner et al., 2004
	DWF1		拟南芥	油菜素内酯合成	Du and Poovaiah, 2005
	LeCBDGK		番茄	磷脂酸合成	Snedden and Blumwald, 2000
	PsTic32		豌豆	叶绿体蛋白移动	Chigri et al., 2006
其它CBPs	MPCBP		玉米	花粉萌发	Safadi et al., 2000
	ZmSAUR1		玉米	生长素信号	Yang and Poovaiah, 2000a; Knauss et al., 2003
	Ch-CPN10		拟南芥	未知	Yang and Poovaiah, 2000b
	NPG1		拟南芥	花粉萌发	Golovkin and Reddy, 2003
	KCBP		拟南芥	细胞分裂, 表皮毛形成	Reddy et al., 1996; Reddy et al., 2004
	DRL1		拟南芥	分裂组织活性, 器官生长	Nelissen et al., 2003
	UBP6		拟南芥	未知	Moon et al., 2005
	IQM1		拟南芥	气孔运动	Zhou et al., 2012