植物学报 ›› 2016, Vol. 51 ›› Issue (6): 849-858.DOI: 10.11983/CBB15149

• 专题论坛 • 上一篇    下一篇

植物铜转运蛋白的结构和功能

袁金红1,2, 李靖锐2,3, 张海燕1,2,,A;*()   

  1. 1天津师范大学生命科学学院, 天津 300387
    2中国科学院植物研究所北方资源植物重点实验室, 北京 100093
    3山西师范大学生命科学学院, 临汾 041000
  • 收稿日期:2015-08-14 接受日期:2016-02-01 出版日期:2016-11-01 发布日期:2016-12-02
  • 通讯作者: 张海燕
  • 作者简介:

    # 共同第一作者

  • 基金资助:
    国家自然科学基金(No.31470292, No.31270313)

Structure and Function of Copper Transporters in Plants

Jinhong Yuan1,2, Jingrui Li2,3, Haiyan Zhang1,2*   

  1. 1College of Life Sciences, Tianjin Normal University, Tianjin 300387, China
    2Key Laboratory of Plant Resources, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
    3School of Life Sciences, Shanxi Normal University, Linfen 041000, China
  • Received:2015-08-14 Accepted:2016-02-01 Online:2016-11-01 Published:2016-12-02
  • Contact: Zhang Haiyan
  • About author:

    # Co-first authors

摘要: 铜(Cu)是植物必需的微量营养元素, 参与植物生长发育过程中的许多生理生化反应。Cu缺乏或过量都会影响植物的正常新陈代谢过程。因此, 植物需要一系列Cu转运蛋白协同作用以保持体内Cu离子的稳态平衡。通常, Cu转运蛋白可分为两类, 即吸收型Cu转运蛋白(如COPT、ZIP和YSL蛋白家族)和排出型Cu转运蛋白(如HMA蛋白家族), 主要负责Cu离子的跨膜转运及调节Cu离子的吸收和排出。然而, 最近有研究表明, 有些Cu伴侣蛋白家族可能是从Cu转运蛋白家族进化而来, 且它们在维持植物细胞Cu离子稳态平衡中也具重要功能。该文对Cu转运蛋白和Cu伴侣蛋白的表达、结构、定位及功能等研究进展进行综述。

Abstract: Copper (Cu) is an essential micronutrient involved in many physiological and biochemical reactions in growth and development in plants. Cu deficiency or excess can affect plant metabolism. Therefore, a series of Cu transporters are needed to act synergistically to sustain Cu homeostasis in plants. Plant Cu transporters can be classified into 2 general classes — Cu-uptake transporters (e.g., COPT, ZIP and YSL protein families) and Cu-efflux transporters (e.g., HMA protein family) — responsible for membrane transport of Cu and mediating Cu uptake and efflux. Recent studies have shown that some Cu chaperone protein families may be evolved from Cu transporter protein families, and Cu chaperones play an important role in maintaining Cu homeostasis. Here, we review developments in the expression, structure, location and function of Cu transporters as well as Cu chaperones.